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HUMULIN 70/30 is the brand name for insulin isophane human and insulin human and is available as a subcutaneous injection.

HUMULIN 70/30 is available as a vial and Kwikpen that contains 100 units/ml.

HUMULIN 70/30 is an insulin and is used to treat the following:

• Type 1 diabetes
• Type 2 diabetes

HUMULIN 70/30 is a mixture of two insulins: 70% insulin NPH (intermediate-acting insulin) and 30% insulin regular (regular-acting insulin). Insulin is a natural hormone your body normally makes to lower glucose (sugar) levels in the blood. A combination of an intermediate-acting and a regular-acting insulin helps to meet your body’s insulin needs throughout the day as well as during meals.

• Humulin 70/30 is injected underneath the skin (subcutaneously) twice per day. The number of units of insulin is different for each person. It depends on whether you are using it for type 1 diabetes or type 2 diabetes, your weight, how well you respond to insulin, and your blood sugar levels
• Your healthcare provider will provide you with directions on how many units of insulin to inject, how to check your own blood sugar levels, and how to make any necessary adjustments in your insulin dose

HUMULIN 70/30 is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of hypoglycemia.

Common side effects of HUMULIN 70/30:

• Low blood sugar
• Reaction or redness at the site of injection
• Allergic reactions
• Fat deposits under the skin
• Weight gain
• Swelling in legs
• Headache

Serious side effects are rare with HUMULIN 70/30. Contact your healthcare provider immediately if you experience any of the following.

• Severe hypoglycemia (dangerously low blood sugar) – If not treated, severe hypoglycemia can lead to unconsciousness, seizures, and even death
• Severe allergic reactions
• Dangerously low levels of potassium

The following medications may interact with HUMULIN 70/30:

• Drugs that may increase the risk of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g. octreotide), and sulfonamide antibiotics
• Drugs that may decrease the blood glucose lowering effect: atypical antipsychotics, corticosteroids, danazol, diuretics estrogens, glucagon, isoniazid, niacin, oral contraceptives phenothiazines, progestogens (e.g., in oral contraceptives) protease inhibitors, somatropin, sympathomimetic agents (e.g. albuterol, epinephrine, terbutaline), and thyroid hormones
• Drugs that may increase or decrease the blood glucose lowering effect: alcohol, beta-blockers, clonidine, lithium salts, and pentamidine
• Drugs that may blunt the signs and symptoms of hypoglycemia: beta-blockers, clonidine, guanethidine, and reserpine

Eli Lilly & Company

HUMULIN 70/30Published studies with HUMALOG U-200 used during pregnancy have not reported an association between insulin lispro and the induction of major birth defects, miscarriage, or adverse maternal or fetal outcomes. If you become pregnant while receiving HUMALOG U-200, talk to your healthcare provider.

• Human Insulin Isophane Suspension/Human Insulin Injection