Used for Cancer

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Manufactured by Genentech, Inc.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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HERCEPTIN cost saving options available to you

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HERCEPTIN Uses, Side Effects, Interactions, Warnings & Dosing



HERCEPTIN is the brand name for trastuzumab IV infusion.

What dosages is HERCEPTIN available in?

What dosages is HERCEPTIN available in?

HERCEPTIN is available as a 440 mg multidose vial.

What is HERCEPTIN used for?

What is HERCEPTIN used for?

HERCEPTIN is a monoclonal antibody that is used to treat:

  • HER2-positive, breast cancers – IV and SQ injections
  • HER2-positive, metastatic stomach cancer – IV injection only
How does HERCEPTIN work?

How does HERCEPTIN work?

HERCEPTIN is a monoclonal antibody that acts as a human epidermal growth factor receptor 2 (HER2) inhibitor. It blocks a specific protein in the body that’s important for cell growth called HER2. HER2 is found on both normal and cancer cells. Cancer cells usually have more HER2 proteins than normal cells. This can cause cancer cells to grow more quickly than normal cells. When HER2 is blocked by HERCEPTIN, cancer cells can’t grow and spread as well.

How do I take HERCEPTIN?

How do I take HERCEPTIN?

HERCEPTIN is given by a healthcare provider as an injection into a vein (IV) or as an injection under the skin (subcutaneous, SQ). When given IV, the dose depends on your body weight. Your healthcare provider will determine the appropriate dose for you each time you receive the medication.

HER2-positive, breast cancers

  • IV injection: The typical dose is 4 mg/kg of bodyweight IV for the first injection, and then 2 mg/kg given once a week. It can also be given as 8 mg/kg for the first injection, and then 6 mg/kg every 3 weeks thereafter
  • SQ injection (Herceptin Hylecta brand only): Herceptin Hylecta for injection under the skin contains trastuzumab and hyaluronidase. The typical dose is 600 mg/10,000 units (trastuzumab/hyaluronidase) given under the skin every 3 weeks. The SQ injection is a flat dose and isn’t dependent on weight.
  • HER2-positive, metastatic stomach cancer: The typical dose is 8 mg/kg IV for the first injection, and then 6 mg/kg every 3 weeks thereafter
Is it safe for me to take HERCEPTIN?

Is it safe for me to take HERCEPTIN?

HERCEPTIN is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

HERCEPTIN Common Side Effects

HERCEPTIN Common Side Effects

Common side effects of HERCEPTIN:

  • Body and joint pain
  • Weakness
  • Fever
  • Nausea
  • Chills
  • Headache
  • Cough
  • Diarrhea
  • Vomiting
  • Infection
HERCEPTIN Serious Side Effects

HERCEPTIN Serious Side Effects

Serious side effects are rare with HERCEPTIN. Contact your healthcare provider immediately if you experience any of the following.

  • Heart problems: chest pain, racing heartbeat, shortness of breath that usually worsens with activity or while lying flat, swelling of your legs or feet, sudden weight gain, fatigue
  • Serious infusion reactions: trouble breathing, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting
  • Lung problems: shortness of breath, trouble breathing
  • Serious infections (when receiving in combination with chemotherapy): repeated fevers, chills, sweating, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
Effects of other drugs, drug classes and over-the-counter products on HERCEPTIN

Effects of other drugs, drug classes and over-the-counter products on HERCEPTIN

  • There are no major drug interactions listed for HERCEPTIN. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes HERCEPTIN?

Who makes HERCEPTIN?

Genentech, Inc.

Is HERCEPTIN safe in pregnancy?

Is HERCEPTIN safe in pregnancy?

HERCEPTIN can cause embryo-fetal harm when administered during pregnancy. Females of reproductive potential to use effective contraception during treatment with HERCEPTIN and for 7 months following the last dose of HERCEPTIN.
There is a pregnancy pharmacovigilance program for HERCEPTIN. If HERCEPTIN is administered during pregnancy, or if a patient becomes pregnant while receiving HERCEPTIN or within 7 months following the last dose of HERCEPTIN, health care providers and patients should immediately report HERCEPTIN exposure to Genentech at 1-888-835-2555.


What to do if you missed your HERCEPTIN dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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