GLEEVEC
Used for Cancer
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Manufactured by Novartis Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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GLEEVEC Uses, Side Effects, Interactions, Warnings & Dosing
What is GLEEVEC?
GLEEVEC is the brand name for imatinib and is available as an oral tablet.
What dosages is GLEEVEC available in?
GLEEVEC is available as a 100 mg and 400 mg oral tablet.
What is GLEEVEC used for?
GLEEVEC is a tyrosine kinase inhibitor and is used to treat Philadelphia chromosome-positive chronic myeloid leukemia, ph+ acute lymphoblastic leukemia, myelodysplastic or myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome or chronic eosinophilic leukemia, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
How does GLEEVEC work?
GLEEVEC is a tyrosine kinase inhibitor (TKI). It blocks a certain protein in your body called tyrosine kinase. This helps stop cancer cells from growing and multiplying.
How do I take GLEEVEC?
GLEEVEC is typically dosed 400 mg or 600 mg by mouth once daily in adults, depending on the condition being treated. Children’s dose will be based on their height and weight. The daily dose is taken by mouth, either as a single dose or as 2 equally separated doses during the day. The maximum dose is 600 mg per day.
Is it safe for me to take GLEEVEC?
GLEEVEC is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
GLEEVEC Common Side Effects
Common side effects of GLEEVEC include:
- Fluid retention or swelling
- Nausea
- Muscle cramps
- Bone, muscle, or joint pain
- Diarrhea
- Rash or other skin reaction
- Fatigue or tiredness
- Headache
- Stomach pain
- Common cold
- Bleeding
- Vomiting
GLEEVEC Serious Side Effects
Serious side effects are rare with GLEEVEC. Contact your healthcare provider immediately if you experience any of the following.
- Infections: fever, chills
- Heart failure: shortness of breath, dry cough, irregular heartbeats, chest pain, weight gain
- Liver damage: yellowing of the skin or eyes, dark urine, tiredness
- Stomach bleed: blood in vomit, black or tarry stools, bright red blood mixed with stools
- Serious skin reactions: rash, hives, peeling skin, blisters
Effects of other drugs, drug classes and over-the-counter products on GLEEVEC
The following medications may interact with GLEEVEC:
- CYP3A4 inducers – May decrease GLEEVEC levels and effects
- CYP3A4 inhibitors – May increase GLEEVEC levels and effects
- GLEEVEC is an inhibitor of CYP3A4 and CYP2D6 which may increase the levels and effects of other drugs. Patients who require anticoagulation should receive low-molecular weight or standard heparin and not warfarin
Who makes GLEEVEC?
Novartis Pharmaceuticals
Is GLEEVEC safe in pregnancy?
GLEEVEC can cause harm to your unborn baby if taken while pregnant based on human and animal data. You should take a pregnancy test before starting treatment and use effective contraception during GLEEVEC treatment and for fourteen days after stopping GLEEVEC. Notify your physician if you are or think you may be pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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