Key facts about Ezetimibe
What dosages is Ezetimibe available in?
Ezetimibe is available as a 10 mg oral tablet.
What is Ezetimibe used for?
Ezetimibe is a cholesterol absorption inhibitor and is used for the treatment of high cholesterol in certain people.
How does Ezetimibe work?
Ezetimibe is a cholesterol absorption inhibitor. It works by lowering the amount of “bad” cholesterol (called LDL) that’s absorbed from your gut.
How do I take Ezetimibe?
Ezetimibe is typically taken as 10 mg by mouth once per day with or without food.
Is it safe for me to take Ezetimibe?
Ezetimibe is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:
- Hypersensitivity to Ezetimibe or any excipient of Ezetimibe. (4)
- When used in combination with a statin, fenofibrate, or other LDL-C lowering therapy, Ezetimibe is contraindicated in patients for whom a statin, fenofibrate, or other LDL-C lowering therapy are contraindicated
Ezetimibe Common Side Effects
Common side effects of Ezetimibe:
- Upper respiratory tract infection
- Diarrhea
- Joint pain
- Inflamed sinuses
- Pain in arms or legs
Ezetimibe Serious Side Effects
Serious side effects are rare with Ezetimibe.
Effects of other drugs, drug classes and over-the-counter products on Ezetimibe
The following medications may interact with Ezetimibe:
- Cyclosporine: Combination increases exposure of Ezetimibe and cyclosporine. Cyclosporine concentrations should be monitored in patients taking Ezetimibe concomitantly
- Fibrates: Coadministration of Ezetimibe with fibrates other than fenofibrate is not recommended until use in patients is adequately studied. If cholelithiasis is suspected in a patient receiving Ezetimibe and fenofibrate, gallbladder studies are indicated, and alternative lipidlowering therapy should be considered
- Bile Acid Sequestrants: Cholestyramine combination decreases exposure of Ezetimibe
Who makes Ezetimibe?
Various FDA-approved generic manufacturers
Is Ezetimibe safe in pregnancy?
It is not known if Ezetimibe will harm your unborn baby. You and your doctor will have to decide if you should take Ezetimibe while you are pregnant or if you plan to become pregnant.
