Used for Cancer

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Manufactured by Eli Lilly & Company

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

ERBITUX Uses, Side Effects, Interactions, Warnings & Dosing

What is ERBITUX?

What is ERBITUX?

ERBITUX is the brand name for cetuximab and is available as an injection for IV use.

What dosages is ERBITUX available in?

What dosages is ERBITUX available in?

ERBITUX is available as a 100 mg/50 mL (2 mg/mL) or 200 mg/100 mL (2 mg/mL) injection for IV use.

What is ERBITUX used for?

What is ERBITUX used for?

ERBITUX is an EGFR inhibitor and is used for the following:

  • Head and neck cancer in certain adults
  • Colorectal cancer in certain adults
How does ERBITUX work?

How does ERBITUX work?

ERBITUX is a monoclonal antibody that acts as an epidermal growth factor receptor (EGFR) inhibitor. It blocks certain proteins from attaching to a specific target on cells called the epidermal growth factor receptor (EGFR). EGFR is found on both normal and cancer cells, and is important for cell growth. Cancer cells usually have more EGFR proteins than normal cells. When EGFR is blocked by ERBITUX, cancer cells can’t grow and spread as well.

How do I take ERBITUX?

How do I take ERBITUX?

  • ERBITUX is an injection into a vein (intravenous, IV) that’s given by a healthcare provider. The dose depends on your body surface area (BSA), which takes into account your body weight and height. Your healthcare provider will determine the appropriate dose for you each time you receive the medication
  • The typical dose is 400 mg/m2 for the first injection, and then 250 mg/m2 given once a week. It can also be given as 500 mg/m2 for the first injection and then every other week thereafter
Is it safe for me to take ERBITUX?

Is it safe for me to take ERBITUX?

ERBITUX is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ERBITUX Common Side Effects

ERBITUX Common Side Effects

Common side effects of ERBITUX:

  • Acne-like rash
  • Fatigue or weakness
  • Diarrhea
  • Nausea
  • Dry skin
  • Itching
  • Vomiting
ERBITUX Serious Side Effects

ERBITUX Serious Side Effects

Serious side effects are rare with ERBITUX. Contact your healthcare provider immediately if you experience any of the following.

  • Serious infusion reactions: throat tightness, trouble breathing, cough, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting
  • Heart attack: chest pain, arm pain, fast or irregular heartbeat, shortness of breath, dizziness, cold sweat, sudden collapse
  • Severe skin reactions: painful blisters, skin wounds, peeling skin, painful sores in your mouth or around your eyes
  • Infections: repeated fevers, chills, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
Effects of other drugs, drug classes and over-the-counter products on ERBITUX

Effects of other drugs, drug classes and over-the-counter products on ERBITUX

  • There are no major drug interactions listed for ERBITUX. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes ERBITUX?

Who makes ERBITUX?

Eli Lilly & Company

Is ERBITUX safe in pregnancy?

Is ERBITUX safe in pregnancy?

Based on animal data and its mechanism of action, ERBITUX can cause fetal harm when administered to a pregnant
woman. If you can become pregnant, you should use effective contraception during treatment with ERBITUX and for 2 months after the last dose of ERBITUX.


What to do if you missed your ERBITUX dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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