ELREXFIO
Used for Cancer
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Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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ELREXFIO Uses, Side Effects, Interactions, Warnings & Dosing
What is ELREXFIO?
ELREXFIO is the brand name for elranatamab-bcmm subcutaneous injection.
What dosages is ELREXFIO available in?
ELREXFIO is available as a 76 mg/1.9 mL (40 mg/mL) or
44 mg/1.1 mL (40 mg/mL) in a single-dose vial.
What is ELREXFIO used for?
ELREXFIO is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T‑cell engager indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
How does ELREXFIO work?
ELREXFIO works by helping your immune system slow or stop the spread of cancer cells.
How do I take ELREXFIO?
ELREXFIO is started low and they gradually increased up to 76 mg biweekly in week 25.
Is it safe for me to take ELREXFIO?
ELREXFIO is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
ELREXFIO Common Side Effects
Common side effects of ELREXFIO:
- Tiredness
- Injection site reaction, such as redness, itching, pain, bruising, rash, swelling, tenderness
- Diarrhea
- Muscle and bone pain
- Decreased appetite
- Rash
- Cough
- Nausea
- Fever
ELREXFIO Serious Side Effects
Serious side effects are rare with ELREXFIO. Tell your healthcare provider right away if you develop any signs or symptoms of an infection during treatment with ELREXFIO. Also let them know if you symptoms of liver problems such as tiredness, loss of appetite, pain in your right upper stomach-area (abdomen), dark urine, and yellowing of your skin or the white part of your eyes.
Effects of other drugs, drug classes and over-the-counter products on ELREXFIO
The following medications may interact with ELREXFIO:
- For certain CYP substrates, minimal changes in the concentration may lead to serious adverse reactions. Monitor for toxicity or drug concentrations of such CYP substrates when co-administered with ELREXFIO
- ELREXFIO causes release of cytokines that may suppress activity of cytochrome P450 (CYP) enzymes, resulting in increased exposure of CYP substrates. Increased exposure of CYP substrates is more likely to occur after the first dose of ELREXFIO Day 1 and up to 14 days after the 32 mg dose on Day 4 and during and after CRS
Who makes ELREXFIO?
Pfizer
Is ELREXFIO safe in pregnancy?
ELREXFIO may harm your unborn baby.
Females who are able to become pregnant:
- Your healthcare provider should do a pregnancy test before you start treatment with ELREXFIO
- You should use effective birth control (contraception) during treatment and for 4 months after your last dose of ELREXFIO
- Tell your healthcare provider right away if you become pregnant or think that you may be pregnant during treatment with ELREXFIO
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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