Used for Depression

View EFFEXOR XR savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or EFFEXOR XR Patient Assistance Program.

Programs are suitable for individuals who want to buy EFFEXOR XR without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Wyeth Pharmaceuticals

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about EFFEXOR XR



EFFEXOR XR is the brand name for venlafaxine and is available as an extended-release oral capsule.

What dosages is EFFEXOR XR available in?

What dosages is EFFEXOR XR available in?

EFFEXOR XR is available as a 37.5 mg, 75 mg, and 150 mg extended-release capsule.

What is EFFEXOR XR used for?

What is EFFEXOR XR used for?

EFFEXOR XR is a SNRI and is used to treat major depressive disorder, anxiety, social anxiety disorder, and panic disorder.

How does EFFEXOR XR work?

How does EFFEXOR XR work?

EFFEXOR XR is a serotonin and norepinephrine reuptake inhibitor (SNRI). It raises serotonin and norepinephrine activity in the brain, which helps adjust your mood.

How do I take EFFEXOR XR?

How do I take EFFEXOR XR?

EFFEXOR XR is typically taken by mouth once daily. The maximum daily dose is 225 mg a day.

Is it safe for me to take EFFEXOR XR?

Is it safe for me to take EFFEXOR XR?

EFFEXOR XR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to venlafaxine hydrochloride, desvenlafaxine succinate, or any excipients in the product, or have taken an MAOI in the past 14 days.

EFFEXOR XR Common Side Effects

EFFEXOR XR Common Side Effects

Common side effects of EFFEXOR XR include:

  • Nausea
  • Feeling tired, fatigued, or sleepy
  • Dry mouth
  • Constipation
  • Sexual problems
  • Loss of appetite
  • Sweating
EFFEXOR XR Serious Side Effects

EFFEXOR XR Serious Side Effects

Serious side effects are rare with EFFEXOR XR. Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction
  • Unusual mood changes
  • Suicidal thoughts or behaviors
  • Blurred vision, eye pain, or changes in vision
  • Chest pain
  • Seizure
  • Shortness of breath
  • Easy bruising or bleeding
  • Blood in urine or stools
  • Serotonin syndrome
Effects of other drugs, drug classes and over-the-counter products on EFFEXOR XR

Effects of other drugs, drug classes and over-the-counter products on EFFEXOR XR

The following medications may interact with EFFEXOR XR:

  • Other serotonergic drugs – Increases the risk of serotonin syndrome
  • Antiplatelet or anticoagulant drugs – May increase the risk of bleeding
  • CYP3A inhibitors – May increase the risk of toxicity of EFFEXOR XR
Who makes EFFEXOR XR?

Who makes EFFEXOR XR?

Wyeth Pharmaceuticals

Is EFFEXOR XR safe in pregnancy?

Is EFFEXOR XR safe in pregnancy?

EFFEXOR XR may increase the risk for preeclampsia when used during mid to late pregnancy. If you become pregnant while receiving EFFEXOR XR, talk to your healthcare provider. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants, including EFFEXOR XR, during pregnancy. Healthcare providers are encouraged to register patients by calling the National Pregnancy Registry for Antidepressants at 1-844-405-6185 or visiting online at women’s health


What to do if you missed your EFFEXOR XR dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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