DUOBRII

This medication is a combination product designed to treat psoriasis, a specific skin condition. It consists of two active ingredients: halobetasol and tazarotene. Halobetasol is a potent corticosteroid that effectively reduces itching, redness, scaling, and swelling associated with psoriasis.

Duobrii Lotion is a topical medication that combines the ingredients halobetasol and tazarotene. Halobetasol is a very strong steroid.

You can use Duobrii Lotion for as long as necessary, but it is important to discontinue use once your psoriasis has cleared and as advised by your doctor. After treatment, your skin may remain clear for up to 3 months. If you experience any side effects, please consult your doctor.

Duobrii is a combination of a steroid and a retinoid. You can purchase it for as low as $985.73, which is 19% off the average retail price of $1,211.60 for the most common version, by using a NowPatient Rx Advantage Card.

To ensure safe usage, patients are advised to apply a thin layer of DUOBRII Lotion once daily, specifically on the affected areas, and gently massage it into the skin. It is important to note that the total amount applied should not exceed approximately 50g per week, as this drug has the potential to suppress the hypothalamic-pituitary-adrenal (HPA) axis.

Plaque psoriasis is the most prevalent type of the disease, but it’s important to be aware of the various other types. Please note that DUOBRII Lotion is specifically approved for treating adults with plaque psoriasis. If you identify any of the symptoms mentioned below, it is advisable to consult your doctor.

You may begin to see improvement with topical products within 1 to 2 weeks, and a reduction in psoriasis symptoms within 4 to 6 weeks. However, for more severe cases of psoriasis and when using stronger medications such as methotrexate, it may take up to 6 months to achieve complete clearing.

In contrast, eczema commonly appears in the skin’s folds and creases, such as behind the knees, on the neck, in the arm creases, and on the face. On the other hand, psoriasis typically manifests on the outer surface of the skin, specifically in areas like the scalp, front of knees, and belly button.

Duobrii stands out as the sole FDA-approved topical steroid-retinoid combination with dermatologic indication, giving it a distinct advantage. Researchers are suggesting the potential off-label use of Duobrii for the treatment of early-mild AKN.

The combination product Duobrii is composed of halobetasol propionate (HP) and tazarotene (TAZ) lotion. It contains a topical superpotent corticosteroid (0.01% w/w HP) and a retinoid product (0.045% w/w TAZ).

Please only use this medication on areas of skin that are affected by psoriasis plaques. Do not apply the lotion to your face, scalp, underarms, or the spaces between your fingers and toes.

Diabetes and psoriasis are both common conditions with a range of serious potential complications. They often occur together as comorbidities, with each one increasing the risk of the other. For example, diabetes is a known risk factor for psoriasis, and vice versa.

Halobetasol and tazarotene topical is a powerful combination medication used to effectively treat plaque psoriasis in adults. Halobetasol is a potent steroid, while tazarotene is a compound similar to vitamin A. This topical treatment helps alleviate the symptoms of plaque psoriasis, including raised, silvery flaking and redness of the skin.

Potency Strength Brand Name Generic Name
Super-potent Ultra-high Psorcon Ointment, 0.05% Augmented diflorasone diacetate
Psorcon E Ointment, 0.05% Diflorasone diacetate
Vanos Cream, 0.1% Fluocinonide
Cordran Tape, 4mcg/sq. cm. Flurandrenolide 4 mcg/cm2

You can purchase mild corticosteroids like clobetasone and hydrocortisone skin cream over the counter at pharmacies for conditions like piles and itchy bottom. However, stronger types such as beclometasone, betamethasone, clobetasol, fluticasone, and mometasone can only be obtained with a prescription.

Do not use this medicine on your face, underarms, or groin area. Avoid getting the medicine in your eyes, mouth, or vagina. Duobrii Lotion may increase your sensitivity to sunlight and cause sunburn. Stay away from sunlight or tanning beds.

Currently, there is no therapeutically equivalent alternative to Duobrii available in the United States. It is important to be cautious of fraudulent online pharmacies that may try to sell illegal generic versions of Duobrii, as these medications could be counterfeit and potentially unsafe.

Halobetasol is considered a super-high to high-potency topical corticosteroid, while triamcinolone is classified as medium-to-low potency. These medications are available in various forms including creams, lotions, ointments, sprays, and shampoos.

Do not use ultra-high-potency topical steroids for more than three weeks continuously, and avoid using low- to high-potency topical steroids for more than three months to prevent side effects.

Duobrii (halobetasol / tazarotene) may require several weeks to show results on your skin. Approximately 10% of individuals experienced noticeable improvements, achieving either clear or nearly clear skin, within two weeks of using Duobrii (halobetasol / tazarotene).

The price of a 100-gram supply of Duobrii topical lotion (0.01%-0.045%) can vary, but it is typically around $1,071, depending on the pharmacy you choose.

Halobetasol is a super-high potency corticosteroid medication used to effectively treat a range of skin conditions including eczema, dermatitis, psoriasis, and rash. It works by reducing swelling, itching, and redness commonly associated with these conditions.

Steroid creams or ointments, known as topical corticosteroids, are frequently prescribed for the treatment of mild to moderate psoriasis on various parts of the body. These medications effectively alleviate inflammation, thereby slowing down the excessive production of skin cells and relieving itching. Topical corticosteroids come in a range of strengths, from mild to highly potent.

According to recent research in 2021, it has been found that thick and oily emollients, such as Vaseline, are beneficial for individuals with psoriasis. These emollients are effective in protecting the skin’s barrier function, which is responsible for shielding the body from external elements and retaining moisture.

Treatment typically leads to improvement in symptoms within one to two weeks. In cases of psoriasis flare-ups, more potent medications like mometasone are commonly used.

The majority of patients experience a reduction in psoriasis symptoms within four to six weeks, and complete clearing may take up to six months. Although it can be highly effective, it is important to note that not all treatments are effective for everyone. In certain cases, combining multiple treatments may yield the most optimal outcomes.

For adults and children 12 years and older, apply to the affected skin area twice a day for a maximum of 2 weeks. Not recommended for children under 12 years of age.

DUOBRII Lotion is a prescription medication containing halobetasol propionate and tazarotene. It is used topically to treat plaque psoriasis in adults.

Duobrii Lotion is a topical medication that combines the ingredients halobetasol and tazarotene. Halobetasol is a very strong steroid.

Hydrocortisone is a gentler type of steroid available in cream and ointment formats, such as Cortizone-10. Urea aids in the softening and removal of psoriasis scales. Some products that contain urea include Eucerin Urea Enriched Roughness Relief Cream and CeraVe Psoriasis Moisturizing Cream.

DUOBRII, the first and only topical approved by the FDA in 2019, combines two active ingredients that have anti-inflammatory benefits to effectively limit plaque growth.

After 24 hours, there was no significant difference in wheal suppression between halobetosol ointment, cream, and clobetasol ointment. However, clobetasol cream was found to be the least effective. It is worth noting that halobetasol is a super-potent topical corticosteroid with an additional fluorine at the 6?± position compared to clobetasol.

Potency StrengthBrand NameGeneric NameSuper-potent Ultra-highLexette Foam, 0.05%Halobetasol propionateUltravate Cream/Ointment, 0.05%Halobetasol propionateUltravate Lotion, 0.05%Halobetasol propionateBryhali Lotion, 0.01%Halobetasol propionate

After 2 weeks of treatment with Duobril, around 10% of people show improvement of their skin. After 8 weeks of treatment with Duobrii over 40% of people show improvement.