Key facts about Duobrii
What is Duobrii?
Duobrii is the brand name for halobetasol propionate and tazarotene and is available as a topical lotion.
What dosages is Duobrii available in?
Duobrii is available as a topical lotion that contains 0.01% of halobetasol propionate
and 0.045% of tazarotene per gram.
What is Duobrii used for?
Duobrii is a corticosteroid / retinoid and is used to treat plaque psoriasis in adults.
How does Duobrii work?
Duobrii is a combination of two medications that work together to treat plaque psoriasis. Halobetasol is a corticosteroid. It lowers inflammation and relieves redness, itching, and swelling of your skin. Tazarotene is a retinoid. It’s unclear how this medication works for plaque psoriasis, but it might be due to changes in skin cell growth and lowering inflammation.
How do I take Duobrii?
Apply a thin layer once a day to cover the affected areas and rub in gently. The maximum dose is 50 grams per week.
Is it safe for me to take Duobrii?
Duobrii is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are pregnant.
Duobrii Common Side Effects
Common side effects of Duobrii:
- Skin rash
- Pain where the medication was applied
- Inflamed hair follicles (folliculitis)
- Thinning of the skin
- Picking of the skin
Duobrii Serious Side Effects
Serious side effects are rare with Duobrii.
Effects of other drugs, drug classes and over-the-counter products on Duobrii
There are no major drug interactions listed for Duobrii. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Duobrii?
Bausch Health
Is Duobrii safe in pregnancy?
Duobrii may cause birth defects if used during pregnancy.
Females must not be pregnant when they start using Duobrii or become pregnant during treatment with Duobrii.
For females who are able to get pregnant:
Your healthcare provider will order a pregnancy test for you within 2 weeks before you begin treatment with Duobrii to be sure that you are not
pregnant. Your healthcare provider will decide when to do the test.
Begin treatment with Duobrii during a normal menstrual period.
Use an effective form of birth control during treatment with Duobrii. Talk with your healthcare provider about birth control options that may be used
to prevent pregnancy during treatment with Duobrii.
Stop using Duobrii and tell your healthcare provider right away if you become pregnant during treatment with Duobrii.













