Key facts about Dornase Alfa
What dosages is Dornase Alfa available in?
Dornase Alfa is available as a 2.5 mg/2.5 mL inhalation solution.
What is Dornase Alfa used for?
Dornase Alfa is a mucolytic that is used to improve lung function in children and adults with cystic fibrosis.
How does Dornase Alfa work?
Dornase Alfa is a mucolytic. It breaks down DNA that builds up to cause thick mucus in the lungs. This makes the mucus thinner, looser, and easier to cough up, so that you can breathe better.
How do I take Dornase Alfa?
Dornase Alfa The typical dose is one 2.5 mg ampule (vial) inhaled once daily using a nebulizer device. Your healthcare provider might raise your dose to 2.5 mg twice a day depending on your response to the medication.
Is it safe for me to take Dornase Alfa?
Dornase Alfa is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Dornase Alfa is contraindicated in patients with known hypersensitivity to
Dornase Alfa, Chinese Hamster Ovary cell products, or any component of the product.
Dornase Alfa Common Side Effects
Common side effects of Dornase Alfa:
- Sore throat
- Fever
- Stuffy nose
- Chest pain
- Change in voice
Dornase Alfa Serious Side Effects
Serious side effects are rare with Dornase Alfa.
Effects of other drugs, drug classes and over-the-counter products on Dornase Alfa
- Available data indicate there are no clinically important drug-drug interactions with Dornase Alfa
Who makes Dornase Alfa?
Various FDA-approved generic manufacturers
Is Dornase Alfa safe in pregnancy?
It is not known if Dornase Alfa will harm your unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using Dornase Alfa.













