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Dornase Alfa is available as a 2.5 mg/2.5 mL inhalation solution.

Dornase Alfa is a mucolytic that is used to improve lung function in children and adults with cystic fibrosis.

Dornase Alfa is a mucolytic. It breaks down DNA that builds up to cause thick mucus in the lungs. This makes the mucus thinner, looser, and easier to cough up, so that you can breathe better.

Dornase Alfa The typical dose is one 2.5 mg ampule (vial) inhaled once daily using a nebulizer device. Your healthcare provider might raise your dose to 2.5 mg twice a day depending on your response to the medication.

Dornase Alfa is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Dornase Alfa is contraindicated in patients with known hypersensitivity to
Dornase Alfa, Chinese Hamster Ovary cell products, or any component of the product.

Common side effects of Dornase Alfa:

• Sore throat
• Fever
• Stuffy nose
• Chest pain
• Change in voice

Serious side effects are rare with Dornase Alfa.

• Available data indicate there are no clinically important drug-drug interactions with Dornase Alfa

Various FDA-approved generic manufacturers

It is not known if Dornase Alfa will harm your unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using Dornase Alfa.

• Pulmozyme