Used for Dementia

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Manufactured by various FDA-approved generic manufacturers.

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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

donepezil Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is donepezil available in?

What dosages is donepezil available in?

donepezil is available as a 5 mg, 10 mg, 23 mg oral tablet and a 5 mg and 10 mg oral disintegrating tablet.

What is donepezil used for?

What is donepezil used for?

donepezil is an acetylcholinesterase inhibitor indicated for the treatment of
dementia of the Alzheimer’s type.

How does donepezil work?

How does donepezil work?

donepezil is a acetylcholinesterase inhibitor. Researchers don’t know exactly how it helps treat Alzheimer’s disease, but the medication prevents the breakdown of a chemical called acetylcholine. Acetylcholine is important in transmitting signals through nerves in the brain for learning and memory.

How do I take donepezil?

How do I take donepezil?

donepezil is typically taken by mouth once daily.

Is it safe for me to take donepezil?

Is it safe for me to take donepezil?

donepezil is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have a known hypersensitivity to donepezil hydrochloride or to piperidine derivatives.

donepezil Common Side Effects

donepezil Common Side Effects

Common side effects of donepezil include:

  • Nausea
  • Diarrhea
  • Headache
  • Trouble sleeping
  • Pain
  • Dizziness
  • Muscle cramps
  • Tiredness
  • Vomiting
  • Loss of appetite
donepezil Serious Side Effects

donepezil Serious Side Effects

Serious side effects are rare with donepezil. Contact your healthcare provider immediately if you experience any of the following.

  • Symptoms of active or occult gastrointestinal (GI) bleeding
  • Seizures
  • Slow heart rate
  • Trouble urinating
Effects of other drugs, drug classes and over-the-counter products on donepezil

Effects of other drugs, drug classes and over-the-counter products on donepezil

The following medications may interact with donepezil:

  • Cholinesterase inhibitors have the potential to interfere with the activity of anticholinergic medications. A synergistic effect may be expected with concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists
Who makes donepezil?

Who makes donepezil?

Various FDA-approved generic manufacturers

Is donepezil safe in pregnancy?

Is donepezil safe in pregnancy?

donepezil may cause harm to your unborn baby, based on animal studies. Talk with your healthcare provider about the risks of taking donepezil if you become pregnant.


What to do if you missed your donepezil dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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