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Dificid is the brand name for fidaxomicin and is available as an oral tablet and suspension.

Dificid is available as a 200 mg oral tablet and a 40 mg/ml oral suspension.

Dificid is a macrolide antibiotic and is used to treat clostridioides difficile-associated diarrhea (commonly called “C. diff”).

Dificid belongs to a group of antibiotics called macrolide antibiotics. It treats your infection by targeting C. difficile bacteria and stopping them from producing important nutrients they need to survive.

Dificid is typically dosed as follows:

• Adults: Take 200 mg (1 tablet) by mouth two times a day for 10 days.
• Children over 6 months old (dose based on weight):
• Children weighing more than 12.5 kg (27.5 lbs): Give 200 mg (5 mL) by mouth two times a day for 10 days.
• Children weighing between 9 kg and 12.5 kg (20-27.5 lbs): Give 160 mg (4 mL) by mouth two times a day for 10 days
• Children weighing between 7 kg and 9 kg (15-20 lbs): Give 120 mg (3 mL) by mouth two times a day for 10 days
• Children weighing between 4 kg and 7 kg (9-15 lbs): Give 80 mg (2 mL) by mouth two times a day for 10 days

Dificid is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Dificid is contraindicated in patients who have known hypersensitivity to
fidaxomicin or any other ingredient in Dificid.

Common side effects of Dificid:

• Fever
• Nausea
• Vomiting
• Stomach pain
• Rash
• Constipation

Serious side effects are rare with Dificid. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reactions

There are no major drug interactions listed for Dificid. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Merck & Co., Inc.

It is not known if Dificid can harm your unborn baby. Dificid should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.

• Fidaxomicin