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Delafloxacin is available in a single-dose vial containing 300 mg of Delafloxacin (equivalent to 433 mg Delafloxacin meglumine) and a 450 mg (equivalent to 649 mg Delafloxacin meglumine) oral tablet.

Delafloxacin is an antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP) in adults.

Delafloxacin is a fluoroquinolone antibiotic. It works by stopping bacteria from copying their DNA, which kills the bacteria and clears the infection.

Delafloxacin for injection is given as 300 mg by intravenous infusion over 60 minutes, every 12 hours,. You can also give a 450 mg tablet orally every 12 hours for 5 to 14 days total duration.

Delafloxacin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Known hypersensitivity to Delafloxacin or other fluoroquinolones

Common side effects of Delafloxacin:

• Diarrhea
• Nausea
• Headache
• Increased liver enzymes
• Vomiting

Serious side effects are rare with Delafloxacin. Contact your healthcare provider immediately if you experience any of the following:

• Serious allergic reaction: rash, hives, swollen face or tongue, tightness in the throat, trouble breathing, fast heartbeat, fainting
• Infectious diarrhea: stomach cramps, fever, watery diarrhea, diarrhea that doesn’t go away, bloody stools
• Blood vessel problems: sudden and severe pain in the back, chest, or abdomen
• Tendon problems: pain and swelling in the back of the ankle, shoulder, hand, or other joints
• Nerve problems: pain, burning, tingling, numbness, weakness
• Nervous system problems: seizures, hallucinations, tremors, anxiety, confusion, depression, suicidal thoughts or behavior, paranoia, memory problems, trouble sleeping, abnormal thoughts

The following medications may interact with Delafloxacin:

• Antacids containing aluminum or magnesium, sucralfate, iron, or with multivitamins containing iron or zinc

Various FDA-approved generic manufacturers

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.