darunavir/cobicistat/emtricitabine/tenofovir/alafenamide
Used for HIV
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Manufactured by various FDA-approved generic manufacturers.
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darunavir/cobicistat/emtricitabine/tenofovir/alafenamide Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is darunavir/cobicistat/emtricitabine/tenofovir/alafenamide available in?
darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is available as an oral tablet that contains 800 mg of darunavir, 150 mg of cobicistat, 200 mg of emtricitabine, and 10 mg of tenofovir alafenamide (equivalent to 11.2 mg of tenofovir alafenamide
fumarate).
What is darunavir/cobicistat/emtricitabine/tenofovir/alafenamide used for?
- darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is a HIV ARV combination that is used to treat HIV
How does darunavir/cobicistat/emtricitabine/tenofovir/alafenamide work?
darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is an HIV ARV combination medication. It contains four different medications that work together to prevent HIV from infecting your cells and making copies of itself:
Darunavir is a protease inhibitor (PI) and blocks an enzyme HIV needs to make copies of itself. Cobicistat is a booster medication. It doesn’t act on HIV. Instead, it slows down your body’s ability to break down darunavir, so that darunavir levels stay higher.
Emtricitabine and tenofovir are nucleoside reverse transcriptase inhibitors (NRTIs). They insert themselves into the virus’ DNA (genetic material) and stop the DNA-making process.
How do I take darunavir/cobicistat/emtricitabine/tenofovir/alafenamide?
- darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is typically taken as 1 tablet by mouth once a day with food
Is it safe for me to take darunavir/cobicistat/emtricitabine/tenofovir/alafenamide?
darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is contraindicated to be co-administered with certain drugs for
which altered plasma concentrations are associated with serious and/or lifethreatening events or which may lead to loss of therapeutic effect of darunavir/cobicistat/emtricitabine/tenofovir/alafenamide and development of resistance.
darunavir/cobicistat/emtricitabine/tenofovir/alafenamide Common Side Effects
Common side effects of darunavir/cobicistat/emtricitabine/tenofovir/alafenamide:
- Diarrhea
- Rash
- Nausea
- Fatigue
- Headache
darunavir/cobicistat/emtricitabine/tenofovir/alafenamide Serious Side Effects
Serious side effects are rare with darunavir/cobicistat/emtricitabine/tenofovir/alafenamide. Contact your healthcare provider immediately if you experience any of the following.
- Liver problems: fever, tiredness, nausea, vomiting, dark urine, clay-colored stool, stomach pain, yellowing of your skin and eyes
- Kidney problems: swelling in your legs and feet, difficulty urinating, confusion
- Severe skin reaction: blistering rash, fever, fatigue, muscle or joint aches, mouth sores
- High blood acid levels (lactic acidosis): muscle pain, severe stomach pain, shallow breathing, tiredness, weakness, change in heartbeat
Effects of other drugs, drug classes and over-the-counter products on darunavir/cobicistat/emtricitabine/tenofovir/alafenamide
The following medications may interact with darunavir/cobicistat/emtricitabine/tenofovir/alafenamide:
- Co-administration of darunavir/cobicistat/emtricitabine/tenofovir/alafenamide with other drugs can alter the concentration of other drugs and other drugs may alter the concentrations of darunavir/cobicistat/emtricitabine/tenofovir/alafenamide components. Consult the full prescribing information prior to and during treatment for potential drug interactions
Who makes darunavir/cobicistat/emtricitabine/tenofovir/alafenamide?
Various FDA-approved generic manufacturers
Is darunavir/cobicistat/emtricitabine/tenofovir/alafenamide safe in pregnancy?
darunavir/cobicistat/emtricitabine/tenofovir/alafenamide is not recommended during pregnancy due to
substantially lower exposures of darunavir and cobicistat during the second and third trimesters of pregnancy.
What to do if you missed your darunavir/cobicistat/emtricitabine/tenofovir/alafenamide dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What is the brand Name for Darunavir Cobicistat emtricitabine tenofovir alafenamide?
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Is darunavir available generic?
What brand is Elvitegravir cobicistat emtricitabine tenofovir alafenamide?
What is the generic for emtricitabine tenofovir alafenamide?
What is the brand name for Darunavir Cobicistat?
What is Darunavir Cobicistat emtricitabine and tenofovir disoproxil?
What is the difference between tenofovir and tenofovir alafenamide?
What is the alternative to darunavir?
What is the difference between ritonavir and cobicistat?
How much does elvitegravir cobicistat emtricitabine tenofovir alafenamide cost?
What company makes darunavir?
When was darunavir approved by the FDA?
What is emtricitabine tenofovir alafenamide used for?
How long does it take for tenofovir and emtricitabine to work?
Is tenofovir emtricitabine a PrEP drug?
Does tenofovir alafenamide cause weight gain?
Is emtricitabine tenofovir risk of liver failure?
When is the best time to take tenofovir and emtricitabine?
How effective is emtricitabine tenofovir PrEP?
What are the side effects of tenofovir alafenamide?
Is tenofovir alafenamide safe?
When is the best time to take tenofovir alafenamide?
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What type of medication is darunavir?
What is Darunavir Cobicistat used for?
What class of drug is cobicistat?
What class of drug is tenofovir?
What class of drug is emtricitabine?
Does darunavir cause weight gain?
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Is there a generic for darunavir?
What is the generic name for darunavir?
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