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Daridorexant is available as a 25 mg and 50 mg oral tablet.

Daridorexant is an orexin antagonist that’s used to help you fall asleep and/or stay asleep.

Daridorexant is an orexin antagonist. It is thought to work by turning down overactive wake signals, one of the biological causes of insomnia, helping you fall asleep and stay asleep.

The recommended dose of Daridorexant is 25 mg to 50 mg once per night, taken by mouth within 30 minutes before going to bed. You should only take Daridorexant if you can get at least 7 hours of sleep before waking up the next day.

Daridorexant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Narcolepsy
• Known hypersensitivity to Daridorexant or other components of Daridorexant

Common side effects of Daridorexant:

• Headache
• Sleepiness or fatigue

Serious side effects are rare with Daridorexant. Contact your healthcare provider immediately if you experience any of the following:

• Excessive sleepiness: daytime sleepiness, trouble focusing or staying alert
• Suicidal thoughts or behaviors
• Depression: anxiety, trouble sleeping, feeling angry or irritated, restlessness
• Abnormal sleep behaviors: sleepwalking, sleep-driving, sleeping during activities, sleep paralysis (temporarily unable to move or talk while waking up)

The following medications may interact with Daridorexant:

• CYP3A4 inhibitors and inducers

Various FDA-approved generic manufacturers

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.

• Quviviq