CINRYZE
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Manufactured by Shire US Inc.
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CINRYZE Uses, Side Effects, Interactions, Warnings & Dosing
What is CINRYZE?
CINRYZE is the brand name for C1 Esterase Inhibitor (Human) that is available as an injection for IV use.
What dosages is CINRYZE available in?
CINRYZE is available as 500 IU of C1 Esterase Inhibitor (Human) for IV use.
What is CINRYZE used for?
CINRYZE is a C1 esterase inhibitor replacement and is used for prevention of hereditary angioedema (HAE) attacks in people 6 years of age and older.
How does CINRYZE work?
CINRYZE is a C1 esterase inhibitor replacement. It contains C1 esterase inhibitor, a protein in your blood that helps relieve swelling (inflammation). Hereditary angioedema (HAE) is a swelling condition caused by low levels of C1 esterase inhibitor. By raising and restoring the levels of C1 esterase inhibitor in the blood, CINRYZE helps prevent swelling attacks from happening in people with HAE.
How do I take CINRYZE?
CINRYZE is dosed as follows:
- Adults and children 12 years and older: The typical dose is 1,000 international units (IU) injected intravenously (into the vein) at a speed of 1 mL/minute (over about 10 minutes) every three or four days. The maximum dose is 2,000 IU, but not more than 80 IU/kg of body weight, every three or four days
- Children 6 to 11 years old: The typical dose is 500 IU injected intravenously at a speed of 1 mL/minute (over about 5 minutes) every three or four days. The maximum dose is 1,000 IU every three or four days
Is it safe for me to take CINRYZE?
CINRYZE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
CINRYZE Common Side Effects
Common side effects of CINRYZE:
- Headache
- Nausea
- Rash
- Vomiting
- Fever
CINRYZE Serious Side Effects
Serious side effects are rare with CINRYZE. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction: hives, chest tightness, difficulty breathing, wheezing, fast heartbeat, swelling of the tongue or throat
- Blood clot: pain, swelling, warmth, or discoloration of the arm or leg, unexplained shortness of breath, chest pain or discomfort, unexplained fast heartbeat, numbness or weakness on one side of the body
Effects of other drugs, drug classes and over-the-counter products on CINRYZE
There are no major drug interactions listed for CINRYZE. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes CINRYZE?
Shire US Inc.
Is CINRYZE safe in pregnancy?
It is not known if CINRYZE can harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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