Key facts about Capmatinib
What dosages is Capmatinib available in?
Capmatinib is available as a 150 mg and 200 mg oral tablet.
What is Capmatinib used for?
Capmatinib is a kinase inhibitor and is used to treat metastatic non-small cell lung cancer (NSCLC) with changes in the MET gene.
How does Capmatinib work?
Capmatinib is a kinase inhibitor. It works by blocking the action of proteins made by the MET gene. When it does, the cancer cells can’t grow and spread as well.
How do I take Capmatinib?
Capmatinib is typically dosed at 400 mg taken by mouth twice daily.
Is it safe for me to take Capmatinib?
Capmatinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Capmatinib Common Side Effects
Common side effects of Capmatinib:
- Lower albumin levels
- Higher creatinine levels
- Swelling of face, arms, or legs
- Nausea
- Lower white and red blood cell counts
- Joint, muscle, and bone pain
- Higher liver enzyme levels
- Tiredness
- Higher digestive enzyme levels
- Vomiting
- Changes in certain electrolyte levels
Capmatinib Serious Side Effects
Serious side effects are rare with Capmatinib. Contact your healthcare provider immediately if you experience any of the following.
- Serious lung problems: dry cough, fever, trouble breathing, taking rapid breaths, chest pain
Effects of other drugs, drug classes and over-the-counter products on Capmatinib
The following medications may interact with Capmatinib:
- Strong and Moderate CYP3A Inducers: Avoid concomitant use
Who makes Capmatinib?
Various FDA-approved generic manufacturers
Is Capmatinib safe in pregnancy?
Capmatinib can harm your unborn baby.
Females who are able to become pregnant:
- Your healthcare provider should do a pregnancy test before you start your treatment with Capmatinib.
- You should use effective birth control during treatment and for 1 week after your last dose of Capmatinib. Talk to your healthcare provider about birth control choices that might be right for you during this time
- Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with Capmatinib.
Males who have female partners who can become pregnant:
- You should use effective birth control during treatment and for 1 week after your last dose of Capmatinib
