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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

BYETTA Uses, Side Effects, Interactions, Warnings & Dosing

What is BYETTA?

What is BYETTA?

BYETTA is the brand name for exenatide and is available as a subcutaneous injection.

What dosages is BYETTA available in?

What dosages is BYETTA available in?

BYETTA is available as 250 mcg/mL exenatide in:

  • 5 mcg per dose, 60 doses, 1.2 mL prefilled pen
  • 10 mcg per dose, 60 doses, 2.4 mL prefilled pen
What is BYETTA used for?

What is BYETTA used for?

BYETTA is a GLP-1 receptor agonist that is used to treat type 2 diabetes, in combination with diet and exercise (adults)

How does BYETTA work?

How does BYETTA work?

BYETTA is a glucagon-like peptide-1 (GLP-1) receptor agonist. It acts like GLP-1, a hormone that tells your body to release insulin after you eat. Also like GLP-1, exenatide blocks your liver from releasing sugar into your blood. These actions help control and maintain blood sugar levels in people with type 2 diabetes.

How do I take BYETTA?

How do I take BYETTA?

The typical dose of BYETTA is 5 to 10 mcg injected under the skin twice a day. Inject within 60 minutes before the two main meals of the day, at least 6 hours apart.

Is it safe for me to take BYETTA?

Is it safe for me to take BYETTA?

BYETTA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2.

BYETTA Common Side Effects

BYETTA Common Side Effects

Common side effects of BYETTA:

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Injection-site lump
  • Constipation
BYETTA Serious Side Effects

BYETTA Serious Side Effects

Serious side effects are rare with BYETTA. Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: rash, hives, trouble breathing, swelling of the face or throat
  • Thyroid cancer: lump in the throat, pain in the neck, jaw, or ear, hoarseness, trouble swallowing or breathing
  • Inflammation of the pancreas (pancreatitis): pain, swelling, or tenderness in the stomach, fever, nausea, vomiting, fast heartbeat
  • Low blood sugar: headache, drowsiness, weakness, hunger, fast heart beat, dizziness, confusion, anxiety, sweating, blurred vision, slurred speech
  • Serious kidney injury: nausea, vomiting, diarrhea, changes in urinary frequency, swelling in legs or ankles, tiredness, shortness of breath
  • Serious bleeding problems: unusual bleeding, bleeding when you brush your teeth, easy bruising, pinpoint red spots on the skin
Effects of other drugs, drug classes and over-the-counter products on BYETTA

Effects of other drugs, drug classes and over-the-counter products on BYETTA

The following medications may interact with BYETTA:

  • May impact absorption of orally administered medications.
  • Warfarin: Postmarketing reports with exenatide of increased international normalized ratio (INR) sometimes associated withbleeding. Monitor INR frequently until stable upon initiation  ofBYETTA therapy
Who makes BYETTA?

Who makes BYETTA?


Is BYETTA safe in pregnancy?

Is BYETTA safe in pregnancy?

BYETTA may harm your unborn baby. Tell your healthcare provider if you become pregnant while using BYETTA . Talk to your healthcare provider about the best way to control your blood sugar if you plan to become pregnant or while you are pregnant.


What to do if you missed your BYETTA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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