Used for Cancer

View brigatinib savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or brigatinib Patient Assistance Program.

Programs are suitable for individuals who want to buy brigatinib without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

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Updated on 24 Apr 2024

Learn more about brigatinib

What dosages is brigatinib available in?

What dosages is brigatinib available in?

brigatinib is available as 30 mg, 90 mg, and 180 mg oral tablet.

What is brigatinib used for?

What is brigatinib used for?

brigatinib is a kinase inhibitor and is used to treat anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer that has spread to other parts of the body.

How does brigatinib work?

How does brigatinib work?

brigatinib is a targeted anticancer medication that blocks a protein called anaplastic lymphoma kinase (ALK) made by the ALK gene. In people with ALK-positive NSCLC, this gene doesn’t work like it should. It ends up making abnormal proteins and causing cancer. By blocking the abnormal ALK protein, brigatinib can help slow or stop the spread of NSCLC cells that are ALK-positive.

How do I take brigatinib?

How do I take brigatinib?

brigatinib is typically started at 90 mg taken by mouth once daily for a week. After that, your provider will raise your dose to 180 mg once daily. Your dose might be different if you have liver or kidney problems.

Is it safe for me to take brigatinib?

Is it safe for me to take brigatinib?

brigatinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

brigatinib Common Side Effects

brigatinib Common Side Effects

Common side effects of brigatinib:

  • Labs (higher creatine phosphokinase), suggesting muscle damage
  • Abnormal liver labs
  • Abnormal pancreas labs
  • Higher blood sugar
  • Diarrhea
  • Rash
  • Cough
  • Nausea
  • High blood pressure
  • Tiredness
  • Muscle pain
  • Headache
  • Trouble breathing
  • Abnormal kidney labs
brigatinib Serious Side Effects

brigatinib Serious Side Effects

Serious side effects are rare with brigatinib. Contact your healthcare provider immediately if you experience any of the following.

  • Severe lung problems: new or worsening breathing problems (e.g., coughing or trouble breathing), chest pain, or fever
  • Dangerously slow heart beat: Tiredness, weakness, feeling dizzy or confused, feeling faint, trouble breathing, chest pain, getting tired easily during physical activity
  • Serious liver problems: feeling very tired, nausea, vomiting, itchy skin, yellowing of the whites of the eyes or skin, stomach pain and swelling, swelling in the legs or ankles, dark-colored urine, pale-colored stool
Effects of other drugs, drug classes and over-the-counter products on brigatinib

Effects of other drugs, drug classes and over-the-counter products on brigatinib

The following medications may interact with brigatinib:

  • CYP3A Inhibitors: Avoid coadministration of brigatinib with strong or moderate CYP3A inhibitors. If coadministration of a strong or moderate CYP3A inhibitor is unavoidable, reduce the dose of brigatinib
  • CYP3A Inducers: Avoid coadministration of brigatinib with strong or moderate CYP3A inducers. If coadministration of a moderate CYP3A inducer is unavoidable, increase the dose of brigatinib
Who makes brigatinib?

Who makes brigatinib?

Various FDA-approved generic manufacturers

Is brigatinib safe in pregnancy?

Is brigatinib safe in pregnancy?

brigatinib can harm your unborn baby. Your healthcare provider will determine whether or not you are pregnant before you start treatment with brigatinib. Tell your healthcare provider right away if you become pregnant during treatment with brigatinib or think you may be pregnant.
o Females who are able to become pregnant should use effective non-hormonal birth control during treatment
with brigatinib and for at least 4 months after the final dose of brigatinib. Birth control pills (oral contraceptives) and other hormonal forms of birth control may not be effective if used during treatment with brigatinib. Talk to your healthcare provider about birth control choices that are right for you during treatment with brigatinib. Males who have female partners that are able to become pregnant should use effective birth control during treatment with brigatinib and for at least 3 months after the final dose of brigatinib.


What to do if you missed your brigatinib dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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