BREZTRI AEROSPHERE
Used for Chronic Bronchitis and Asthma
NowPatient can significantly lower the cost* of your prescription medication by providing free access to drug coupons, savings cards, patient assistance programs and other out of pocket discount programs. Whether you’re insured, uninsured, or underinsured, we empower you with transparency and cost-saving tools to make your BREZTRI AEROSPHERE more affordable.
Manufactured by AstraZeneca
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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BREZTRI AEROSPHERE key facts
What is BREZTRI AEROSPHERE?
BREZTRI AEROSPHERE is the brand name for budesonide, glycopyrrolate, and formoterol fumarate and is available as a metered dose inhaler.
What dosages is BREZTRI AEROSPHERE available in?
BREZTRI AEROSPHERE is available as a metered dose inhaler containing a combination of budesonide (160 mcg), glycopyrrolate (9 mcg), and formoterol fumarate (4.8 mcg) per inhalation.
What is BREZTRI AEROSPHERE used for?
BREZTRI AEROSPHERE is a IC/ LAMA/LABA that is used to treat chronic obstructive pulmonary disease (COPD).
How does BREZTRI AEROSPHERE work?
BREZTRI AEROSPHERE is a combination of three medications used for COPD that work together to relax and open up the airways in your lungs so you can breathe more easily.
- Budesonide is an inhaled corticosteroid (IC). It lowers inflammation (swelling) in your lungs, which helps control COPD symptoms
- Glycopyrrolate is a long-acting muscarinic antagonist (LAMA). In your lungs, the medication blocks the activity of a natural chemical in your body called acetylcholine. This helps open up your airways, which helps you breathe easier
- Formoterol is a long-acting beta-2 agonist (LABA). It helps relax the muscles in your airways and make it easier to breathe
How do I take BREZTRI AEROSPHERE?
The typical dose of BREZTRI AEROSPHERE is 2 inhalations (or puffs) by mouth twice daily (taken as 2 puffs in the morning and 2 puffs in the evening).
Is it safe for me to take BREZTRI AEROSPHERE?
BREZTRI AEROSPHERE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a hypersensitivity to budesonide, glycopyrrolate, formoterol fumarate, or to any
of the excipients.
BREZTRI AEROSPHERE Common Side Effects
Common side effects of BREZTRI AEROSPHERE:
- Upper respiratory tract infection (common cold, runny nose)
- Pneumonia
- Back pain
- Oral thrush
- Flu
- Muscle spasms
- Urinary tract infection (UTI)
- Cough
- Sinus infection
- Diarrhea
BREZTRI AEROSPHERE Serious Side Effects
Serious side effects are rare with BREZTRI AEROSPHERE. Contact your healthcare provider immediately if you experience any of the following.
- Breathing problems: sudden shortness of breath, difficulty breathing, coughing, wheezing
- Overdose: heart attack, chest pain, fast or abnormal heart rate, dizziness, anxiety, headache, tremor, dry mouth, muscle spasms, nausea, tiredness, hard time sleeping (insomnia)
- Allergic reactions: hives, swelling of the lips, tongue, or throat, rash, difficulty breathing, anaphylaxis (type of allergic reaction)
Effects of other drugs, drug classes and over-the-counter products on BREZTRI AEROSPHERE
The following medications may interact with BREZTRI AEROSPHERE:
- Strong cytochrome P450 3A4 inhibitors (e.g. ritonavir): Use with caution
- May cause systemic corticosteroid effects
- Other adrenergic drugs may potentiate effect: Use with caution
- Diuretics, xanthine derivatives or steroids may potentiate hypokalemia or ECG changes. Use with caution
- Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. May potentiate effect of formoterol fumarate on cardiovascular system
- Beta-blockers: Use with caution. May block bronchodilatory effects of beta-agonists and produce severe bronchospasm
- Anticholinergics: May interact additively with concomitantly used anticholinergic medications. Avoid administration of BREZTRI AEROSPHERE with other anticholinergic-containing drugs
Who makes BREZTRI AEROSPHERE?
AstraZeneca
Is BREZTRI AEROSPHERE safe in pregnancy?
It is not known if BREZTRI AEROSPHERE can harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking BREZTRI AEROSPHERE. You and your healthcare provider will decide if you should take BREZTRI AEROSPHERE while you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my BREZTRI AEROSPHERE prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your BREZTRI AEROSPHERE prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient BREZTRI AEROSPHERE savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient BREZTRI AEROSPHERE savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for BREZTRI AEROSPHERE | Canadian Prescription Savings* for BREZTRI AEROSPHERE | BREZTRI AEROSPHERE Drug Coupon* | BREZTRI AEROSPHERE Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of BREZTRI AEROSPHERE?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for BREZTRI AEROSPHERE | Canadian Prescription Savings* for BREZTRI AEROSPHERE | BREZTRI AEROSPHERE Drug Coupon* | BREZTRI AEROSPHERE Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the BREZTRI AEROSPHERE savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the BREZTRI AEROSPHERE drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for BREZTRI AEROSPHERE, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the BREZTRI AEROSPHERE prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, BREZTRI AEROSPHERE is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed BREZTRI AEROSPHERE for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the BREZTRI AEROSPHERE prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the BREZTRI AEROSPHERE prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for BREZTRI AEROSPHERE
If you are having trouble paying for your BREZTRI AEROSPHERE medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for BREZTRI AEROSPHERE you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- BREZTRI AEROSPHERE is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers BREZTRI AEROSPHERE
- If BREZTRI AEROSPHERE is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for BREZTRI AEROSPHERE
If you are having trouble paying for your BREZTRI AEROSPHERE medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for BREZTRI AEROSPHERE you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers BREZTRI AEROSPHERE
- If BREZTRI AEROSPHERE is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for BREZTRI AEROSPHERE
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your BREZTRI AEROSPHERE treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for BREZTRI AEROSPHERE you will need to meet the following criteria:
- You must be currently insured and have coverage for BREZTRI AEROSPHERE
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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