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Biaxin XL is the brand name of clarithromycin and is available as an extended-release oral tablet.

Biaxin XL is available as a 500 mg extended-release oral tablet.

Biaxin XL macrolide antibiotic used for lung infections related to on-going bronchitis in adults, pneumonia in adults and children, sinus infections in adults and children, strep throat in adults and children, tonsil infections in adults and children, skin infections in adults and children, ear infections in children, treatment and prevention of certain infections in adults with HIV, and stomach ulcers caused by Helicobacter pylori (H. pylori) in adults.

Biaxin XL is a macrolide antibiotic. It works by stopping bacteria from making certain proteins inside their cells. This causes the bacteria to not be able to grow and survive.

Biaxin XL is typically taken by mouth once daily for 7 to 14 days, depending on the type and severity of the infection.

Biaxin XL is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have a known hypersensitivity to clarithromycin, erythromycin, or any of the macrolide antibiotics, a history of cholestatic jaundice/hepatic dysfunction, or currently take cisapride,pimozide, astemizole, terfenadine, and ergotamine or dihydroergotamine.

Common side effects of Biaxin XL include:

• Stomach pain
• Diarrhea
• Nausea
• Vomiting
• Change in taste
• Other Side Effects
• Indigestion
• Allergic reaction
• Fungal infection
• Headache
• Difficulty sleeping
• Rash

Serious side effects are rare with Biaxin XL. Contact your healthcare provider immediately if you experience any of the following.

• Serious allergic or skin reactions: hives, rash, blisters, fever, swelling of the lips or tongue, difficulty breathing, skin reddening, or skin peeling
• Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
• Abnormal heart rhythm (QT prolongation): chest pounding, trouble breathing, chest pain, feeling faint or lightheaded
• Infectious (C. difficile-related) diarrhea: rapid heart rate, foul-smelling diarrhea, fever, nausea, frequent bowel movements (even up to 15 times per day)

The following medications may interact with Biaxin XL:

• CYP3A4 substrates – These include colchicine toxicity with colchicine; rhabdomyolysis with simvastatin, lovastatin, and atorvastatin; and hypotension with calcium channel blockers metabolized by CYP3A4 (e.g., verapamil, amlodipine, diltiazem)

Abbott Pharmaceuticals

Biaxin XL should not be used during pregnancy unless there is no appropriate alternative. If you become pregnant while receiving Biaxin XL, talk to your healthcare provider.

• Clarithromycin