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Betaseron is the brand name for interferon beta-1b subcutaneous injection.

Betaseron is available as a 0.3 mg single-dose vial.

Betaseron is a biologic and is used to treat relapsing forms of multiple sclerosis.

Betaseron is a biologic medication that affects your immune system. The exact way it works to treat multiple sclerosis is unknown.

The typical starting dose is 0.0625 mg (equal to 0.25 mL) injected under the skin every other day. Your provider will raise your dose by 0.0625 mg every 2 weeks until you reach the full recommended dose of 0.25 mg (equal to 1 mL) every other day.

Betaseron is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a history of hypersensitivity to natural or recombinant interferon beta, albumin
or mannitol.

Common side effects of Betaseron:

• Low blood cell counts
• Injection site reactions: pain, swelling, bleeding
• Flu-like symptoms: fever, chills, muscle pain, weakness, sweating
• Muscle weakness
• Headache
• Pain
• Stiff muscles
• Fever
• Muscle pain
• Chills
• Difficulty sleeping
• Rash
• Loss of balance/coordination
• Stomach pain
• Swelling in legs or hands
• Urinating more

Serious side effects are rare with Betaseron. Contact your healthcare provider immediately if you experience any of the following.

• Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion
• Serious allergic reactions: hives, itching, swelling of face or tongue, difficulty breathing
• Heart failure: shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, unable to exercise, tiredness, weakness
• Injection site necrosis (skin cell death): blue-black discoloration, swelling, broken skin
• Serious infections: fever, tiredness, chills, cough, trouble breathing
• Blood problems: purple bruises or pin-point dots on the skin, pale skin, yellowing of the skin or whites of your eyes, fever, tiredness, confusion, difficulty breathing, not able to make urine
• Depression or suicidal ideation
• Seizures

• There are no major drug interactions listed for Betaseron. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

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It is not known if Betaseron will harm your unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using Betaseron.

• Interferon Beta-1b