Key facts about Beqvez
What is Beqvez?
Beqvez is an IV infusion that is used to treat hemophilia B.
What dosages is Beqvez available in?
Beqvez is available as a 1 × 10^13 vg/mL suspension for IV infusion.
What is Beqvez used for?
Beqvez is type of gene therapy used to treat adults with moderate to severe hemophilia B (congenital factor IX deficiency) who: Currently use factor IX prophylaxis therapy, or Have current or historical life-threatening hemorrhage, or Have repeated, serious spontaneous bleeding episodes, and, Do not have neutralizing antibodies to adeno-associated virus serotype Rh74var (AAVRh74var) capsid.
How does Beqvez work?
Beqvez is designed to give your body the healthy (working or functioning) FIX gene it lacks. It uses a vector to carry the working gene to your liver. After Beqvez gets to your liver, it helps your body make more clotting FIX proteins. In hemophilia B, your FIX gene is changed or mutated.
How do I take Beqvez?
Beqvez is dosed based on your weight and then given over a 60 minute IV infusion.
Is it safe for me to take Beqvez?
Beqvez is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Beqvez Common Side Effects
Common side effects of Beqvez: Elevated liver enzymes
Beqvez Serious Side Effects
Serious side effects are rare with Beqvez. Contact your healthcare provider immediately if you experience any of the following: Liver damage: nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine Serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing Infusion reactions: fever, heart palpitations, nausea, vomiting, chills, headache, or signs of low blood pressure (such as dizziness on standing) Increased risk of liver cancer
Effects of other drugs, drug classes and over-the-counter products on Beqvez
No interaction studies have been performed with Beqvez.
Who makes Beqvez?
Pfizer Inc.
Is Beqvez safe in pregnancy?
Beqvez is not intended for use in women. There are no data from the use of Beqvez in pregnant women and no animal studies have been conducted with this medication.
