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Azactam is the brand name for aztreonam and is available as an intravenous or by intramuscular injection.

Azactam is available in a single-dose 15 mL vial that contains 1 gm or 2 gm of aztreonam.

Azactam is an antibiotic that is used to treat:

• Urinary tract infections
• Lower respiratory tract infections
• Bloodstream infectionss
• Skin infections
• Stomach infections
• Infection of the uterine lining

Azactam is a monobactam antibiotic that kills bacteria by preventing them from being able to make a cell wall around them.

Azactam is typically given as an injection into the veins (intravenous or IV) or into the buttock or thigh muscle (intramuscular or IM) by a provider in a healthcare setting (e.g., hospital, office, nursing home).

Adults

Urinary tract infections:

• The typical dose is 500 mg or 1,000 mg IV or IM every 8 or 12 hours.
• Moderate-to-severe infections: The typical dose is 1 gram or 2 grams IV or IM every 8 or 12 hours.
• Severe or life-threatening infections: The typical dose is 2 grams IV or IM every 6 or 8 hours.
• Children
• Your child’s dose is based on your their body weight. The typical dose is 30 mg/kg given IV every 6 or 8 hours.

Azactam is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to aztreonam or any other component in the formulation. known hypersensitivity to aztreonam or any other component in the formulation. known hypersensitivity to aztreonam or any other component in the formulation.

Common side effects of Azactam:

• Injection site reactions
• Diarrhea
• Nausea
• Vomiting
• Rash

Serious side effects are rare with Azactam. Contact your healthcare provider immediately if you experience any of the following:

• Serious allergic reaction: hives, rash, blisters, skin reddening, swelling of the lips or tongue, difficulty breathing
• Infectious diarrhea: foul-smelling diarrhea, frequent bowel movements (up to 15 times per day), fever, stomach pain or cramps

There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Bristol-Myers Squibb

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.

• Aztreonam