Used for Depression

View ANAFRANIL savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or ANAFRANIL Patient Assistance Program.

Programs are suitable for individuals who want to buy ANAFRANIL without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Mallinckrodt Pharmaceuticals

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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Updated on 26 Apr 2024

Learn more about ANAFRANIL



ANAFRANIL is the brand name for clomipramine and is available as an oral capsule.

What dosages is ANAFRANIL available in?

What dosages is ANAFRANIL available in?

ANAFRANIL is available as a 25 mg, 50 mg, and 75 mg capsule.

What is ANAFRANIL used for?

What is ANAFRANIL used for?

ANAFRANIL is a tricyclic antidepressant used to treat obsessive-compulsive disorder (OCD) in patients 10 years of age and older.

How does ANAFRANIL work?

How does ANAFRANIL work?

ANAFRANIL is a tricyclic antidepressant (TCA). It’s believed to help raise the amounts of specific chemicals in the brain, like serotonin. This balancing act helps control behavior, feelings, mood, and thoughts linked to obsessive-compulsive disorder.

How do I take ANAFRANIL?

How do I take ANAFRANIL?

ANAFRANIL is typically started at a low dose and taken once or twice daily. The maximum dose 200 mg/day for children and 250 mg/day for adults.

Is it safe for me to take ANAFRANIL?

Is it safe for me to take ANAFRANIL?

ANAFRANIL is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have taken a monoamine oxidase (MAO) inhibitor within the past 14 days, during the acute recovery phase of a heart attack, or if you are taking linezolid or intravenous methylene blue.

ANAFRANIL Common Side Effects

ANAFRANIL Common Side Effects

Common side effects of ANAFRANIL include:

  • Dry mouth
  • Sleepiness
  • Dizziness
  • Tremor
  • Headache
  • Constipation
  • Sexual problems in males
  • Tiredness
  • Nausea
  • Sweating more
  • Trouble sleeping
ANAFRANIL Serious Side Effects

ANAFRANIL Serious Side Effects

Serious side effects are rare with ANAFRANIL. Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Low sodium level: headache, difficulty concentrating or remembering, weakness, feeling unsteady on your feet, seizure, coma
  • Serotonin syndrome: fast heartbeat, sweating, muscle stiffness or spasms, fever, confusion
  • Serious skin reaction: rash, itching, fever
Effects of other drugs, drug classes and over-the-counter products on ANAFRANIL

Effects of other drugs, drug classes and over-the-counter products on ANAFRANIL

The following medications may interact with ANAFRANIL:

  • MAO Inhibitors – Life-threatening interactions may occur
  • Serotonergic Drugs – Serotonin syndrome has been reported
  • CNS Depressants – Effects of alcohol, barbiturates, and other CNS depressants may be enhanced
Who makes ANAFRANIL?

Who makes ANAFRANIL?

Mallinckrodt Pharmaceuticals

Is ANAFRANIL safe in pregnancy?

Is ANAFRANIL safe in pregnancy?

It is not known if ANAFRANIL will harm your unborn baby. If you become pregnant while receiving ANAFRANIL, talk to your healthcare provider .


What to do if you missed your ANAFRANIL dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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