Key facts about Ambien CR
What is Ambien CR?
Ambien CR is the brand name for zolpidem extended-release tablets.
What dosages is Ambien CR available in?
Ambien CR is available as a 6.25 mg and 12.5 mg extended-release tablets.
What is Ambien CR used for?
Ambien CR is a GABA A receptor positive modulator that is used to treat insomnia.
How does Ambien CR work?
Ambien CR is a gamma-aminobutyric acid (GABA) A receptor positive modulator. It works on GABA receptors in the brain to slow down brain activity. This helps you relax and fall asleep faster.
How do I take Ambien CR?
The typical dose is 6.25 mg to 12.5 mg by mouth nightly at bedtime.
Is it safe for me to take Ambien CR?
Ambien CR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have the following.
Patients who have experienced complex sleep behaviors after taking Ambien CR.
Known hypersensitivity to zolpidem.
Ambien CR Common Side Effects
- Common side effects of Ambien CR:
- Headache
- Sleepiness
- Dizziness
- Diarrhea
Ambien CR Serious Side Effects
Serious side effects are rare with Ambien CR. Contact your healthcare provider immediately if you experience any of the following.
Dangerous sleep behaviors: sleepwalking, sleep driving, or doing any activity while not being fully alert
Slowed brain activity (CNS depression): excessive sleepiness, confusion, coma
Trouble breathing (respiratory depression): shallow breaths, tiredness, slow breaths
Serious allergic reaction: itchy, red rash (hives), shortness of breath, chest tightness, throat closing, nausea, vomiting, swelling of lips, tongue, face, or eyes
Suicidal thoughts and behavior
Effects of other drugs, drug classes and over-the-counter products on Ambien CR
- The following medications may interact with Ambien CR:
- CNS depressants, including alcohol: Possible adverse additive CNS depressant effects.
- Imipramine: Decreased alertness observed.
- Chlorpromazine: Impaired alertness and psychomotor performance
- observed.
- CYP3A4 inducers (e.g. rifampin): Combination use may decrease effect.
- CYP3A4 inhibitors (e.g. ketoconazole): Combination use may increase
- effect.
Who makes Ambien CR?
Sanofi-Aventis U.S.
Is Ambien CR safe in pregnancy?
Based on animal data Ambien CR may cause fetal harm. ell your healthcare provider if you become pregnant while taking Ambien CR.













