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Adacel is the brand name for tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine and is available as an injection given into the shoulder muscle.

Adacel is a single-dose vial or prefilled syringe containing a 0.5 mL suspension for injection.

Adacel is a vaccine use to prevent:

• Tetanus
• Diphtheria
• Pertussis (whooping cough)

Adacel is an inactivated vaccine that helps your body’s immune system make antibodies to protect you from 3 bacteria that cause conditions like Clostridium tetani (tetanus), Corynebacterium diphtheriae (diphtheria), and Bordatella pertussis (pertussis or whooping cough).

Adacel is typically dosed as follows:

For routine vaccination:

• Adacel is given at least 5 years after the last dose of the DTaP vaccine or the Td vaccine.
• If you need a second dose of the vaccine, you should get it at least 8 years after your first dose.

Prevention of tetanus after getting a wound:

• The vaccine is given at least 5 years after receiving another tetanus toxoid-containing vaccine.

Adacel is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• An allergy to any tetanus, diphtheria, or pertussis-containing vaccine (including DT, Td, and DTaP)
• Coma, having seizures for a long time, or lowered level of consciousness within 7 days of a previous dose of a pertussis-containing vaccine

Common side effects of Adacel:

• Injection site reactions
• Headache
• Tiredness
• Body ache or muscle weakness
• Chills
• Joint pain
• Nausea
• Diarrhea

Serious side effects are rare with Adacel. Contact your healthcare provider immediately if you experience any of the following:

• Serious allergic reaction: hives, rash, swelling of your face, tongue or throat, shortness of breath, and chest pain

The following medications may interact with Adacel:

• Other injectable vaccines or Tetanus Immune
• Globulin
• Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic
• Drugs and corticosteroids

Sanofi-Aventis U.S.

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Adacel during pregnancy.

• Tetanus Toxoid, Reduced Diphtheria Toxoid And Acellular Pertussis Vaccine