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Paliperidone

Paliperidone Generic

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AVAILABLE CURRENTLY, ONLY IN
United States
*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Paliperidone ER
    Generic for Invega
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    6mg
    30 extended release tablets $91.5 USD
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  3. Paliperidone ER
    Generic for Invega
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    1.5mg
    12 extended release tablets $36.9 USD
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  4. Paliperidone ER
    Generic for Invega
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    3mg
    12 extended release tablets $36.9 USD
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  5. Paliperidone ER
    Generic for Invega
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    9mg
    15 extended release tablets $46.2 USD
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Do you need a prescription for paliperidone?

Yes, paliperidone is only available with a valid physician Rx.

How much is paliperidone without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase paliperidone, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for paliperidone in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a paliperidone savings card?

Yes. Save up to 90% on your paliperidone with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a paliperidone coupon provider in the US?

No. Now Patient does not provide paliperidone coupons or FREE paliperidone samples.

Do you accept commercial, Medicare or Medicaid coverage for paliperidone in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much paliperidone?

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Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using paliperidone. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much paliperidone. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of paliperidone and manufacturer

Paliperidone is available under the brand names Invega, Invega Sustenna, Invega Trinza, and Invega Hafyera which are manufactured by Janssen Pharmaceuticals, Inc.

UK brand name of paliperidone and manufacturer

In the UK, paliperidone is available under the brand name Xeplion, which is manufactured by Janssen-Cilag Ltd.

Availability of paliperidone

Paliperidone is available by prescription only.

FDA approval of paliperidone

Paliperidone has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia in adults and adolescents aged 12 to 17 years.

NHS prescription (UK) for paliperidone

Paliperidone may be available in the UK with an NHS prescription. It is important to consult with your healthcare provider or pharmacist to verify availability.

Mechanism of action

Paliperidone is an atypical antipsychotic medication. It works by blocking the receptors for dopamine and serotonin in the brain, which helps to regulate the activity of these neurotransmitters. This can help to reduce the symptoms of schizophrenia.

Uses of paliperidone

Paliperidone is primarily used for the treatment of schizophrenia and schizoaffective disorder in adults and adolescents aged 12 to 17 years.

Dosage of paliperidone

Paliperidone palmitate is a long-acting injectable formulation of paliperidone. Your dose of paliperidone may vary depending on your condition. It is important to follow the instructions provided by your healthcare provider. The following is a general guideline for the dosages of paliperidone in the treatment of schizophrenia:

  • Adults: The recommended starting dose is 6 mg once daily, taken orally. The dose may be increased to 9 mg or 12 mg once daily, as determined by the healthcare provider, based on individual response and tolerability
  • Adolescents aged 12 to 17 years: The recommended starting dose is 3 mg once daily, taken orally. The dose may be increased to 6 mg or 9 mg once daily, as determined by the healthcare provider, based on individual response and tolerability

It is important to take paliperidone exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your doctor.

Warnings and precautions for paliperidone

  • Tell a healthcare professional if you are allergic to paliperidone, or risperidone (Risperdal)
  • You will need to have your blood sugar, weight, blood pressure, and cholesterol tested while taking this medication
  • Those with Parkinson’s disease or dementia with Lewy bodies may have an increased sensitivity to treatment with paliperidone
  • Invega is not approved for the treatment of dementia-related psychosis in elderly patients as it may increase the risk of death

Is it safe to take paliperidone if I am pregnant or planning on becoming pregnant?

The safety of paliperidone in pregnancy has not been well established. If you are pregnant, planning to become pregnant, or suspect you may be pregnant, it is important to discuss the use of paliperidone with your healthcare provider. They can evaluate the potential risks and benefits to determine the best course of action for your specific situation.

Is it safe to take paliperidone while breastfeeding?

Paliperidone may pass into breast milk, and its effects on infants are not well known. It is recommended to exercise caution while taking paliperidone if you are breastfeeding. Paliperidone may also increase the production of prolactin. Consult with your healthcare provider for guidance on the potential risks and benefits.

Interactions with other drugs

Paliperidone may have an increased risk for drug interactions in patients taking other antipsychotic drugs such as aripiprazole, chlorpromazine, olanzapine and thioridazine, antidepressants, and other medications that affect the QT interval of the heart. It is important to inform your healthcare provider about all the medications you are taking including vitamins and herbal supplements, to avoid potential interactions.

Side effects

In clinical trials common side effects of paliperidone may include:

  • Drowsiness
  • Sedation
  • Extrapyramidal symptoms/EPS (such as tremors or involuntary muscle movements)
  • Akathisia (restlessness)
  • Weight gain
  • Constipation
  • Muscle stiffness
  • Dry mouth

Paliperidone may cause tardive dyskinesia or neuroleptic malignant syndrome (NMS). It is important to note that this is not a complete list of adverse effects. If you experience any unusual or serious side effects, contact your healthcare provider.

Sources:

Disclaimer

Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
purple check Stefano Mirabello
Pharmacist / B.Pharm
Our Editorial Process
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