RINVOQ
NowPatient can significantly lower the cost* of your prescription medication by providing free access to drug coupons, savings cards, patient assistance programs and other out of pocket discount programs. Whether you’re insured, uninsured, or underinsured, we empower you with transparency and cost-saving tools to make your RINVOQ more affordable.
Manufactured by AbbVie Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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RINVOQ key facts
What is RINVOQ?
RINVOQ is the brand name for upadacitinib and is available as an extended-release oral tablet.
What dosages is RINVOQ available in?
RINVOQ is available as a 15 mg, 30 mg, and 45 mg extended-release oral tablet.
What is RINVOQ used for?
RINVOQ is a JAK inhibitor and is used for the following:
- Rheumatoid arthritis (RA)
- Psoriatic arthritis (PsA)
- Eczema (atopic dermatitis)
- Ulcerative colitis (UC)
- Crohn’s disease (CD)
- Ankylosing spondylitis (AS)
- Non-radiographic axial spondyloarthritis (nr-axSpA)
How does RINVOQ work?
RINVOQ is a janus kinase (JAK) inhibitor. It blocks the JAK enzyme (protein) that plays a role in your immune system to cause inflammation. By blocking this enzyme, RINVOQ is thought to calm down your immune system to relieve symptoms of arthritis and certain inflammatory conditions.
How do I take RINVOQ?
RINVOQ is typically dosed as follows:
- All approved types of arthritis (RA, PsA, AS, and nr-axSpA): The typical dose is 15 mg by mouth once a day
- Eczema: The typical dose is 15 mg by mouth once a day. If you’re between the ages of 12 and 65 and weigh at least 88 lbs, your provider might raise your dose to 30 mg once a day if you’re not seeing an improvement in your symptoms
- Ulcerative colitis: The typical starting dose is 45 mg by mouth once a day for 8 weeks. Then, the recommended maintenance dose is 15 mg once a day thereafter. But if you’re not seeing an improvement in your symptoms and your UC is severe, your provider might raise your maintenance dose to 30 mg once a day
- Crohn’s disease: The typical starting dose is 45 mg by mouth once a day for 12 weeks. Then, the recommended maintenance dose is 15 mg once a day thereafter. But if you’re not seeing an improvement in your symptoms and your CD is severe, your provider might raise your maintenance dose to 30 mg once a day
Your dose might differ if you have kidney or liver problems.
Is it safe for me to take RINVOQ?
RINVOQ is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
RINVOQ Common Side Effects
Common side effects of RINVOQ:
- Upper airway infection (e.g., common cold, strep throat)
- Bronchitis
- Headache
- Cough
- Nausea
- Stomach pain
- Acne
- Rash
- Herpes simplex virus (HSV) infection
- Herpes zoster infection (shingles)
RINVOQ Serious Side Effects
Serious side effects are rare with RINVOQ. Contact your healthcare provider immediately if you experience any of the following.
- Serious infection: fever, shortness of breath, muscle aches, cough, weight loss, painful sores on your skin
- Blood clots: swelling and pain in your arms or legs, warm skin, trouble breathing
- Stroke: slurred speech, trouble walking, numbness on one side of your body or face, drooping face
- Heart attack: chest pain or tightness; pain that radiates up to your shoulder, arm, neck, or jaw
- Stomach tear: stomach pain, nausea, vomiting, blood in your stools
- Serious allergic reactions: hives; swelling of your lips, tongue, or throat; trouble breathing
Effects of other drugs, drug classes and over-the-counter products on RINVOQ
The following medications may interact with RINVOQ:
- Strong CYP3A4 Inhibitors: See the Full Prescribing Information for dosage modification for patients with atopic dermatitis, ulcerative colitis, and Crohn’s disease
- Strong CYP3A4 Inducers: Coadministration of RINVOQ with strong CYP3A4 inducers is not recommended
Who makes RINVOQ?
AbbVie Inc.
Is RINVOQ safe in pregnancy?
Based on findings in animal studies, RINVOQ may cause fetal harm when administered to a pregnant woman. Verify the pregnancy status of females of reproductive potential prior to
starting treatment with RINVOQ. If you can become pregnant, use effective contraception during treatment with RINVOQ and for 4 weeks following completion of therapy.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my RINVOQ prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your RINVOQ prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient RINVOQ savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient RINVOQ savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for RINVOQ | Canadian Prescription Savings* for RINVOQ | RINVOQ Drug Coupon* | RINVOQ Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of RINVOQ?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for RINVOQ | Canadian Prescription Savings* for RINVOQ | RINVOQ Drug Coupon* | RINVOQ Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the RINVOQ savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the RINVOQ drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for RINVOQ, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the RINVOQ prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, RINVOQ is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed RINVOQ for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the RINVOQ prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the RINVOQ prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for RINVOQ
If you are having trouble paying for your RINVOQ medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for RINVOQ you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- RINVOQ is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers RINVOQ
- If RINVOQ is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for RINVOQ
If you are having trouble paying for your RINVOQ medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for RINVOQ you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers RINVOQ
- If RINVOQ is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for RINVOQ
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your RINVOQ treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for RINVOQ you will need to meet the following criteria:
- You must be currently insured and have coverage for RINVOQ
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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