View RINVOQ savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or RINVOQ Patient Assistance Program.

Programs are suitable for individuals who want to buy RINVOQ without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by AbbVie Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

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    Rx Advantage Card

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    Save up to 90%

  • Available

    Canadian Prescription Savings

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  • Unavailable

    Drug Coupons

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    Patient Assistance Programs

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about RINVOQ

What is RINVOQ?

What is RINVOQ?

RINVOQ is the brand name for upadacitinib and is available as an extended-release oral tablet.

What dosages is RINVOQ available in?

What dosages is RINVOQ available in?

RINVOQ is available as a 15 mg, 30 mg, and 45 mg extended-release oral tablet.

What is RINVOQ used for?

What is RINVOQ used for?

RINVOQ is a JAK inhibitor and is used for the following:

  • Rheumatoid arthritis (RA)
  • Psoriatic arthritis (PsA)
  • Eczema (atopic dermatitis)
  • Ulcerative colitis (UC)
  • Crohn’s disease (CD)
  • Ankylosing spondylitis (AS)
  • Non-radiographic axial spondyloarthritis (nr-axSpA)
How does RINVOQ work?

How does RINVOQ work?

RINVOQ is a janus kinase (JAK) inhibitor. It blocks the JAK enzyme (protein) that plays a role in your immune system to cause inflammation. By blocking this enzyme, RINVOQ is thought to calm down your immune system to relieve symptoms of arthritis and certain inflammatory conditions.

How do I take RINVOQ?

How do I take RINVOQ?

RINVOQ is typically dosed as follows:

  • All approved types of arthritis (RA, PsA, AS, and nr-axSpA): The typical dose is 15 mg by mouth once a day
  • Eczema: The typical dose is 15 mg by mouth once a day. If you’re between the ages of 12 and 65 and weigh at least 88 lbs, your provider might raise your dose to 30 mg once a day if you’re not seeing an improvement in your symptoms
  • Ulcerative colitis: The typical starting dose is 45 mg by mouth once a day for 8 weeks. Then, the recommended maintenance dose is 15 mg once a day thereafter. But if you’re not seeing an improvement in your symptoms and your UC is severe, your provider might raise your maintenance dose to 30 mg once a day
  • Crohn’s disease: The typical starting dose is 45 mg by mouth once a day for 12 weeks. Then, the recommended maintenance dose is 15 mg once a day thereafter. But if you’re not seeing an improvement in your symptoms and your CD is severe, your provider might raise your maintenance dose to 30 mg once a day

Your dose might differ if you have kidney or liver problems.

Is it safe for me to take RINVOQ?

Is it safe for me to take RINVOQ?

RINVOQ is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

RINVOQ Common Side Effects

RINVOQ Common Side Effects

Common side effects of RINVOQ:

  • Upper airway infection (e.g., common cold, strep throat)
  • Bronchitis
  • Headache
  • Cough
  • Nausea
  • Stomach pain
  • Acne
  • Rash
  • Herpes simplex virus (HSV) infection
  • Herpes zoster infection (shingles)
RINVOQ Serious Side Effects

RINVOQ Serious Side Effects

Serious side effects are rare with RINVOQ. Contact your healthcare provider immediately if you experience any of the following.

  • Serious infection: fever, shortness of breath, muscle aches, cough, weight loss, painful sores on your skin
  • Blood clots: swelling and pain in your arms or legs, warm skin, trouble breathing
  • Stroke: slurred speech, trouble walking, numbness on one side of your body or face, drooping face
  • Heart attack: chest pain or tightness; pain that radiates up to your shoulder, arm, neck, or jaw
  • Stomach tear: stomach pain, nausea, vomiting, blood in your stools
  • Serious allergic reactions: hives; swelling of your lips, tongue, or throat; trouble breathing
Effects of other drugs, drug classes and over-the-counter products on RINVOQ

Effects of other drugs, drug classes and over-the-counter products on RINVOQ

The following medications may interact with RINVOQ:

  • Strong CYP3A4 Inhibitors: See the Full Prescribing Information for dosage modification for patients with atopic dermatitis, ulcerative colitis, and Crohn’s disease
  •  Strong CYP3A4 Inducers: Coadministration of RINVOQ with strong CYP3A4 inducers is not recommended
Who makes RINVOQ?

Who makes RINVOQ?

AbbVie Inc.

Is RINVOQ safe in pregnancy?

Is RINVOQ safe in pregnancy?

Based on findings in animal studies, RINVOQ may cause fetal harm when administered to a pregnant woman. Verify the pregnancy status of females of reproductive potential prior to
starting treatment with RINVOQ. If you can become pregnant, use effective contraception during treatment with RINVOQ and for 4 weeks following completion of therapy.


What to do if you missed your RINVOQ dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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