rilpivirine
Used for HIV
Are you tired of high medication costs? Our service offers unbeatable savings on your rilpivirine prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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Lower the cost of your rilpivirine prescription
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rilpivirine key facts
What dosages is rilpivirine available in?
rilpivirine is available as a 25 mg oral tablet.
What is rilpivirine used for?
rilpivirine is a HIV ARV and is used for the following:
- Treatment of HIV-1 infection in people with an HIV viral load of less than 100,000 copies/mL and who haven’t taken HIV medications before
- Short-term treatment of HIV-1 infection in certain people who are planning to start or planning to miss a dose of Cabenuva (cabotegravir / rilpivirine)
How does rilpivirine work?
rilpivirine is an HIV antiretroviral medication that’s known as a non-nucleoside reverse transcriptase inhibitor (NNRTI). It blocks an enzyme called reverse transcriptase that helps HIV make copies of itself. By blocking this enzyme, the medication prevents HIV from spreading.
How do I take rilpivirine?
rilpivirine is dosed as follows:
- Treatment of HIV-1: The typical dose is 25 mg by mouth once a day with a meal. rilpivirine is taken with other antiretroviral medications
- Short-term treatment of HIV-1 before starting Cabunuva (cabotegravir / rilpivirine): The typical dose is 25 mg by mouth once a day with a meal for about 1 month (at least 28 days). It’s taken together with Vocabria (cabotegravir)
- Replacing a missed injection of Cabenuva (cabotegravir / rilpivirine): Your HIV specialist might prescribe rilpivirine for you to take for a short while if you’re getting Cabenuva injections for HIV but will miss an injection because of a schedule conflict (e.g., traveling). The typical dose of rilpivirine is 25 mg by mouth once a day with a meal and with Vocabria (cabotegravir). This combination is only meant to be taken for up to 2 months to replace missed injections
Is it safe for me to take rilpivirine?
rilpivirine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you take any medications that can greatly lower the amount of rilpivirine in your body, such as certain anti-seizure medications (e.g., carbamazepine (Tegretol)), certain antibiotics (e.g., rifampin (Rifadin)), more than a single dose of dexamethasone, or St. John’s wort
rilpivirine Common Side Effects
Common side effects of rilpivirine:
- Higher liver function tests
- Higher cholesterol levels
- Higher creatinine levels
- Feeling depressed
- Headache
- Trouble sleeping
- Rash
rilpivirine Serious Side Effects
Serious side effects are rare with rilpivirine. Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts and behaviors
- Serious allergic reactions: mouth sores; trouble breathing; rash; fever; swelling in your face, lips, or tongue
- Liver problems: upper right stomach pain, nausea, yellowing of the skin or whites of the eyes, dark urine
Effects of other drugs, drug classes and over-the-counter products on rilpivirine
The following medications may interact with rilpivirine:
- Consider alternatives to rilpivirine or rilpivirine PED when coadministered with drugs with a known risk of torsade de pointes
- rilpivirine and rilpivirine PED should not be used in combination with NNRTIs
- Coadministration of rilpivirine or rilpivirine PED with drugs that induce or inhibit CYP3A may affect the plasma concentrations of rilpivirine
- Coadministration of rilpivirine or rilpivirine PED with drugs that increase gastric pH may decrease plasma concentrations of rilpivirine
- Refer to the Full Prescribing Information for other drugs that should not be coadministered with rilpivirine or rilpivirine PED and for other drugs that may require a change in dose or regimen
Who makes rilpivirine?
Various FDA-approved generic manufacturers
Is rilpivirine safe in pregnancy?
It is not known if rilpivirine will harm your unborn baby. If you become pregnant while receiving rilpivirine, talk to your healthcare provider. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to
rilpivirine during pregnancy. Healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry (APR) 1-800-258-4263.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my rilpivirine prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your rilpivirine prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient rilpivirine savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient rilpivirine savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for rilpivirine | Canadian Prescription Savings* for rilpivirine | rilpivirine Drug Coupon* | rilpivirine Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of rilpivirine?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for rilpivirine | Canadian Prescription Savings* for rilpivirine | rilpivirine Drug Coupon* | rilpivirine Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the rilpivirine savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the rilpivirine drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for rilpivirine, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the rilpivirine prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, rilpivirine is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed rilpivirine for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the rilpivirine prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the rilpivirine prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for rilpivirine
If you are having trouble paying for your rilpivirine medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for rilpivirine you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- rilpivirine is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers rilpivirine
- If rilpivirine is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for rilpivirine
If you are having trouble paying for your rilpivirine medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for rilpivirine you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers rilpivirine
- If rilpivirine is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for rilpivirine
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your rilpivirine treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for rilpivirine you will need to meet the following criteria:
- You must be currently insured and have coverage for rilpivirine
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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