MAVYRET
Are you tired of high medication costs? Our service offers unbeatable savings on your MAVYRET prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by AbbVie Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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MAVYRET key facts
What is MAVYRET?
MAVYRET is the brand name for glecaprevir and pibrentasvir and is available as an oral tablet and pellets.
What dosages is MAVYRET available in?
MAVYRET is available as an oral tablets that contains 100 mg glecaprevir and 40 mg pibrentasvir and oral pellets that contains 50 mg glecaprevir and 20 mg pibrentasvir.
What is MAVYRET used for?
MAVYRET is an antiviral and is used for the following:
- Chronic (long-term) hepatitis C genotype 1, 2, 3, 4, 5, or 6 infection in certain people age 3 years and older
- Hepatitis C genotype 1 infection in people age 3 years and older who were previously treated with an NS5A inhibitor or an HCV protease inhibitor (not both)
How does MAVYRET work?
MAVYRET contains two antiviral medications that work together to stop the hepatitis C virus (HCV) from making copies of itself in the body. The two medications are glecaprevir (a protease inhibitor) and pibrentasvir (an NS5A inhibitor). They work by attacking two different proteins in the virus. Using two medications that work in different ways can prevent HCV resistance, which is when the virus develops a defense against antivirals. As a result, the medications no longer work to fight the virus.
How do I take MAVYRET?
MAVYRET is dosed as follows:
- Adults, children age 12 years or older, and children who weigh at least 99 pounds: The recommended dose is 3 tablets by mouth once a day with food. The total daily dose is 300 mg of glecaprevir and 120 mg of pibrentasvir
- Children age 3 to 12 years old: The dose is based on your child’s body weight. The provider will determine the right dose for your child. In general, the recommended dose ranges from 3 to 5 packets of oral pellets by mouth once a day with food
- The treatment duration ranges from 8 to 16 weeks, depending on your previous HCV treatment regimens and your liver health
Is it safe for me to take MAVYRET?
MAVYRET is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Patients with moderate or severe hepatic impairment (Child-Pugh B or C) or those with any history of prior hepatic decompensation
- Coadministration with atazanavir or rifampin
MAVYRET Common Side Effects
Common side effects of MAVYRET:
- Headache
- Fatigue or tiredness
- Nausea
MAVYRET Serious Side Effects
Serious side effects are rare with MAVYRET. Contact your healthcare provider immediately if you experience any of the following.
- Liver failure caused by hepatitis B virus reactivation: nausea, stomach pain, yellowing of your skin or whites of your eyes
Effects of other drugs, drug classes and over-the-counter products on MAVYRET
The following medications may interact with MAVYRET:
- Carbamazepine, efavirenz, and St. John’s wort may decrease concentrations of glecaprevir and pibrentasvir. Coadministration of carbamazepine efavirenz containing regimens, and St. John’s wort with MAVYRET is not
- recommended
- Clearance of HCV infection with direct-acting antivirals may lead to changes in hepatic function, which may impact safe and effective use of concomitant medications. Frequent monitoring of relevant laboratory parameters (INR or blood glucose) and dose adjustments of certain concomitant medications may be necessary
- Medication- Assisted Treatment (MAT) for Opioid Use Disorder
- Consult the full prescribing information prior to and during treatment for potential drug interactions
Who makes MAVYRET?
AbbVie Inc.
Is MAVYRET safe in pregnancy?
No adequate human data are available to establish whether or not MAVYRET poses a risk to pregnancy outcomes. MAVYRET should be administered during pregnancy only if the potential benefit justifies the potential risk to the fetus.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my MAVYRET prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your MAVYRET prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient MAVYRET savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient MAVYRET savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for MAVYRET | Canadian Prescription Savings* for MAVYRET | MAVYRET Drug Coupon* | MAVYRET Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of MAVYRET?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for MAVYRET | Canadian Prescription Savings* for MAVYRET | MAVYRET Drug Coupon* | MAVYRET Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the MAVYRET savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the MAVYRET drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for MAVYRET, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the MAVYRET prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, MAVYRET is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed MAVYRET for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the MAVYRET prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the MAVYRET prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for MAVYRET
If you are having trouble paying for your MAVYRET medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for MAVYRET you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- MAVYRET is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers MAVYRET
- If MAVYRET is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for MAVYRET
If you are having trouble paying for your MAVYRET medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for MAVYRET you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers MAVYRET
- If MAVYRET is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for MAVYRET
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your MAVYRET treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for MAVYRET you will need to meet the following criteria:
- You must be currently insured and have coverage for MAVYRET
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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In the UK, we are located at:
NowPatient
28 Chipstead Valley Road
Coulsdon
Surrey
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NowPatient
8911 North Capital of Texas Highway
Suite 4200 #1263
78759
Austin, TX
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UK telephone number – 020 388 51 500
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Who owns NowPatient?
NowPatient is owned and operated by Infohealth Ltd, a licensed online pharmacy with services spanning the UK, US and Rest of the World. Infohealth Ltd is registered in England and Wales under company number 04004930 and our registered office is at Lynwood House, 373 – 375 Station Road, Harrow, England, HA1 2AW.
Our website is www.nowpatient.com. Our App is called “NowPatient” and can be downloaded from the App Store (for Apple devices) or Google Play (for Android devices).
Can you tell me more about your NHS online pharmacy?
NowPatient’s Pharmaceutical services in the UK are provided by Infohealth Limited trading as ‘Infohealth Pharmacy’.
Our dispensing pharmacy is regulated and authorized for internet sales by the General Pharmaceutical Council (GPhC), registration number 1036487. You can view our license credentials on the General Pharmaceutical Council website. Our superintendent pharmacist who is responsible for the safe and effective oversight of medicines supplies is Mr Amish Patel (Registration Number 2042705).
Medicines are not ordinary items of commerce. All medicines or healthcare product sales are made under the supervision of a registered pharmacist who is licensed by the GPhC. At all times, we endeavour to provide a professional and transparent service whose primary goal is to ensure that the best interests of the patient are served.
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Our prescribing services are regulated by the General Pharmaceutical Council (GPhC). We provide the following regulated activity:
• treatment of disease, disorder, or injury
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NowPatient prescribing services are run by Infohealth Limited. The Clinical Safety Officer and nominated individual is Mr Navin Khosla.
Can you tell me more about NowPatient’s US services?
Our head of US services is Dr. Jamie Winn.
You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
We do not provide any prescribing services or dispensing services in the United States.
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