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Insulin Glargine is available as a KwikPen and Tempo Pen with a strength of 100 units/mL (U-100).

Insulin Glargine is an insulin and is used to treat the following:

• Type 1 diabetes in adults and children
• Type 2 diabetes in adults

Insulin Glargine is an insulin. Insulin is a hormone that lowers glucose (sugar) levels in the blood. It helps your body absorb and store sugar from your bloodstream and stops your liver from making glucose.

Insulin Glargine is typically dosed as follows:

• Type 1 diabetes: The typical starting dose is 33% of your total daily insulin requirement injected under the skin once daily. Follow your provider’s instructions carefully. Insulin Glargine should be used with a short-acting or rapid-acting, pre-meal insulin to meet the the remainder of your daily insulin requirements
• Type 2 diabetes: The typical starting dose is 0.2 units/kg or up to 10 units injected under the skin once daily

Insulin Glargine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of hypoglycemia (low blood sugar).

Common side effects of Insulin Glargine:

• Infection
• Common cold
• Respiratory tract infection

Serious side effects are rare with Insulin Glargine. Contact your healthcare provider immediately if you experience any of the following.

• Severe hypoglycemia (dangerously low blood sugar): if not treated, it can lead to unconsciousness, seizures, and even death
• Severe allergic reactions: problems breathing, blistering skin rash with a high fever, or if you feel your face, mouth, or throat swell up
• Low potassium levels: weakness, muscle cramps or twitches, digestive problems, abnormal heartbeats, kidney problems

The following medications may interact with Insulin Glargine:

• Drugs that may increase the risk of hypoglycemia: antidiabeticagents, ACE inhibitors, angiotensin II receptor blocking agents disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors
• pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g.octreotide), and sulfonamide antibiotics
• Drugs that may decrease the blood glucose lowering
• effect: atypical antipsychotics, corticosteroids, danazol, diuretics estrogens, glucagon, isoniazid, niacin, oral contraceptives phenothiazines, progestogens (e.g., in oral contraceptives)protease inhibitors, somatropin, sympathomimetic agents (e.g. albuterol, epinephrine, terbutaline), and thyroid hormones
• Drugs that may increase or decrease the blood glucose lowering effect: alcohol, beta-blockers, clonidine, lithium salts, and pentamidine
• Drugs that may blunt the signs and symptoms of
• hypoglycemia: beta-blockers, clonidine, guanethidine, and reserpine

Various FDA-approved generic manufacturers

Published studies with use of Insulin Glargine products during pregnancy have not reported a clear association with
Insulin Glargine and adverse developmental outcomes. You and your doctor will have to decide if you should take BASGLAR while you are pregnant or if you plan to become pregnant.

• Basaglar
• Lantus
• Toujeo