Amantadine Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Amantadine HCl
    Generic for Symmetrel
    30 capsules $6 USD
    Save $44.10
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Do you need a prescription for amantadine?

Yes, amantadine is only available with a valid physician Rx.

How much is amantadine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase amantadine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for amantadine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a amantadine savings card?

Yes. Save up to 90% on your amantadine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a amantadine coupon provider in the US?

No. Now Patient does not provide amantadine coupons or FREE amantadine samples.

Do you accept commercial, Medicare or Medicaid coverage for amantadine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much amantadine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using amantadine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much amantadine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic amantadine?

Generic amantadine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of amantadine

Amantadine is approved by the U.S. Food and Drug Administration (FDA) for the treatment and prevention of influenza A virus infections. It is also used off-label for the treatment of Parkinson’s disease and other movement disorders.

Active ingredient of amantadine

The active ingredient of amantadine is amantadine hydrochloride.

US brand name of amantadine and manufacturer

Amantadine is available in the US under the brand name Symmetrel. It is manufactured by Endo Pharmaceuticals.

UK brand name of amantadine and manufacturer

In the UK, amantadine is available under the brand name PK-Merz. The manufacturer may vary depending on the brand name.

Prescription requirement for amantadine

A prescription (Rx) is required for amantadine in both the US and the UK.

Availability of amantadine in the UK with NHS prescription

Amantadine is available in the UK with an NHS prescription.

Conditions treated by amantadine

Amantadine is a medication that can help improve motor function in individuals with Parkinson’s disease. It can also be used for the conditions; influenza treatment, fatigue reduction in Multiple Sclerosis. In addition to its approved uses, amantadine is sometimes prescribed off-label for other conditions such as chronic pain or drug-induced extrapyramidal symptoms. However, it’s important to consult a healthcare professional before considering any off-label use of amantadine due to potential risks and side effects.

How does amantadine work?

Amantadine is an adamantane antiviral drug.

  • Amantadine works by affecting the levels of certain neurotransmitters in the brain
  • Amantadine is a weak, noncompetitive NMDA receptor antagonist
  • By reducing the activity of this receptor, amantadine helps to alleviate symptoms associated with Parkinson’s disease and influenza A
  • As an antiparkinsonian medication, it can be used alone or as an adjunct therapy alongside other medications to manage motor symptoms such as tremors and stiffness
  • Additionally, its antiviral properties make it an effective treatment of influenza A virus

Forms of amantadine available

Amantadine is available in the following dosage forms: as a capsule, extended-release capsule, tablet, extended-release tablet and liquid to take by mouth.

Dosage of amantadine

The dosage of amantadine may vary depending on the specific condition being treated and individual patient factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for amantadine use

Amantadine should be taken exactly as directed by the healthcare provider. The capsules or oral solution are usually taken orally, with or without food. It is important to take amantadine consistently and at regular intervals for the best results. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Warnings and precautions for amantadine

  • Amantadine may have certain risks and potential side effects. It is important to discuss these with a healthcare provider before starting the medication. Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma, kidney disease, mental/mood conditions such as depression, and psychosis
  • It is important to follow the prescribed dosage and not exceed the recommended duration of treatment to avoid the development of resistance
  • Inform your doctor about all medications you are currently taking. It is important to be aware of drug interactions with amantadine that lead to adverse effects. Examples of such medications include anticholinergic drugs like benztropine or trihexyphenidyl

Use of amantadine if pregnant or planning pregnancy

The use of amantadine during pregnancy and breastfeeding should be discussed with a healthcare provider. It should be used during pregnancy only if the potential benefits outweigh the risks.

Possible side effects of amantadine

Common side effects of amantadine may include drowsiness, lightheadedness, positional low blood pressure (low blood pressure when you stand), nausea, constipation and dry mouth. Serious side effects are possible such as livedo reticularis,  but less common. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to amantadine

Other antiviral medications used for the treatment and prevention of influenza A virus infections include, oseltamivir and zanamivir. For Parkinson’s disease and movement disorders, other medications such as levodopa-carbidopa and dopamine agonists may be prescribed.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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