AKLIEF Prices, Discounts & Coupons
Used for Acne
NowPatient can significantly lower the cost* of your prescription medication by providing free access to drug coupons, savings cards, patient assistance programs and other out of pocket discount programs. Whether you’re insured, uninsured, or underinsured, we empower you with transparency and cost-saving tools to make your AKLIEF more affordable.
Manufactured by Galderma Laboratories, L.P.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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Lower the Cost of Your AKLIEF Prescription
Rx Advantage Card
Our savings card can be used in over 65,000 pharmacies and could save you up to 90% on the cost of your medication. Suitable for insured, underinsured and uninsured individuals. This is not health insurance and cannot be used in conjunction with insurance.
Drug Coupons
For those who are commercially insured, drug manufacturer coupons can help reduce your out-of-pocket costs. Eligible for commercially insured only.
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Patient Assistance Programs
Patient assistance programs (PAPs) are sponsored by pharmaceutical companies and can mean you can obtain your medications at no cost to you. Suitable for insured, underinsured and uninsured individuals who are financially constrained.
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MEDICAL INFORMATION
AKLIEF Key Facts
What is AKLIEF?
AKLIEF is the brand name for trifarotene and is available as a topical cream application.
What dosages is AKLIEF available in?
AKLIEF is available as a 0.005% cream application.
What is AKLIEF used for?
AKLIEF (trifarotene) is a prescription topical retinoid cream approved for the treatment of acne vulgaris in individuals aged 9 years and older. It is particularly effective for both facial and truncal acne, including areas such as the chest, shoulders, and back.
How does AKLIEF work?
AKLIEF is a retinoid; specifically, a fourth-generation elective retinoic acid receptor (RAR)-γ agonist that helps accelerate the skin’s natural cell turnover, exfoliating dead cells and helping to prevent new acne breakouts. It may also reduce the inflammation commonly associated with pimples.
How do I take AKLIEF?
Aklief (trifarotene) is a prescription topical retinoid used to treat acne vulgaris on the face, chest, shoulders, and back. To use it effectively and safely, follow these steps:
Step 1: Cleanse
- Wash the affected areas with a mild or soap-free cleanser.
- Gently pat the skin dry.
Step 2: Apply Aklief
- Apply once daily in the evening.
- Use a thin layer:
- Face: 1 pump (covers forehead, cheeks, nose, and chin).
- Upper trunk (shoulders, chest, upper back): 2 pumps.
- Middle/lower back: 1 additional pump if needed.
- Avoid contact with eyes, lips, mouth, corners of the nose, and mucous membranes.
- Wash your hands after application.
Step 3: Moisturize
- Apply a moisturizer as needed to minimize dryness and irritation.
- You can apply it before or after Aklief; ensure the skin is dry between applications.
Step 4: Protect from Sunlight
- Minimize sun exposure.
- Use sunscreen with SPF 15 or higher and wear protective clothing over treated areas.
Additional Tips
- Do not apply to cuts, abrasions, sunburned skin, or areas affected by eczema.
- Avoid using other skin products that may cause irritation, such as medicated or abrasive soaps and cleansers, products with high alcohol content, or other acne treatments unless directed by your healthcare provider.
- Avoid waxing on treated areas.
- If you miss a dose, apply it the next evening. Do not double up on doses.
Is it safe for me to take AKLIEF?
AKLIEF is a safe and effective treatment when used for FDA-licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
AKLIEF Common Side Effects
Most side effects are mild and tend to diminish with continued use. Side effects of AKLIEF may include:
- Redness (erythema)
- Dryness
- Scaling
- Stinging or burning sensation
- Itching (pruritus)
- Sunburn
AKLIEF Serious Side Effects
Serious side effects are rare with AKLIEF. Contact your healthcare provider immediately if you experience any of the following.
- Severe Skin Irritation: This can manifest as intense redness, burning, stinging, scaling, or swelling at the application site. These reactions are more common during the initial weeks of treatment and may decrease over time.
- Increased Sensitivity to Sunlight: Aklief can heighten your skin’s sensitivity to ultraviolet (UV) light, leading to a higher risk of sunburn. It’s advisable to minimize sun exposure and use sunscreen with a high SPF. Medical News Today
- Allergic Reactions: Though rare, some individuals may experience allergic reactions, including skin rash, itching, hives, or swelling of the face, lips, tongue, or throat.
Effects of other drugs, drug classes and over-the-counter products on AKLIEF
Other Topical Retinoids: Using Aklief alongside other topical retinoids (e.g., tretinoin, adapalene) can increase skin irritation.
Benzoyl Peroxide Products: Combining Aklief with benzoyl peroxide may lead to excessive skin dryness and irritation.
Salicylic Acid Products: Concurrent use with salicylic acid can enhance skin irritation.
Isotretinoin (Oral Retinoid): Using Aklief with isotretinoin may increase the risk of skin irritation.
Photosensitizing Agents: Medications like aminolevulinic acid, methoxsalen, porfimer, and verteporfin can increase sensitivity to sunlight when used with Aklief.
Astringents and Abrasive Products: Products such as medicated or abrasive soaps, cleansers, and cosmetics with strong skin-drying effects can exacerbate skin irritation when used with Aklief.
Who makes AKLIEF?
Galderma Laboratories, L.P.
Is AKLIEF safe in pregnancy?
It is not known if AKLIEF will harm your unborn baby. If you become pregnant while receiving AKLIEF, talk to your healthcare provider since the data are limited, and caution is advised.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the US
Drug Savings Guide
A Practical Guide to Saving Money and Receiving Support With Prescription Drug Costs
How can NowPatient help me to lower the cost of my AKLIEF prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your AKLIEF prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient AKLIEF savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient AKLIEF savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for AKLIEF | Canadian Prescription Savings* for AKLIEF | AKLIEF Drug Coupon* | AKLIEF Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of AKLIEF?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for AKLIEF | Canadian Prescription Savings* for AKLIEF | AKLIEF Drug Coupon* | AKLIEF Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the AKLIEF savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the AKLIEF drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for AKLIEF, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the AKLIEF prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, AKLIEF is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed AKLIEF for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the AKLIEF prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the AKLIEF prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for AKLIEF
If you are having trouble paying for your AKLIEF medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for AKLIEF you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- AKLIEF is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers AKLIEF
- If AKLIEF is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for AKLIEF
If you are having trouble paying for your AKLIEF medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for AKLIEF you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers AKLIEF
- If AKLIEF is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for AKLIEF
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your AKLIEF treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for AKLIEF you will need to meet the following criteria:
- You must be currently insured and have coverage for AKLIEF
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.