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Zylet is the brand name for loteprednol etabonate/tobramycin ophthalmic suspension.

Zylet is available as an ophthalmic suspension that contains 0.5% of loteprednol etabonate and 0.3% of tobramycin.

Zylet is an antibiotic / corticosteroid and is used fir the following:

• Inflamed eyes that have a bacterial infection
• Inflamed eyes that could become infected with bacteria

Zylet contains two ingredients that work together to treat or prevent inflammation and bacterial infections of the eye. Loteprednol, a corticosteroid, lessens eye inflammation and relieves eye pain. Tobramycin, an antibiotic, prevents bacteria from making the nutrients they need to survive.

Place 1 to 2 drops inside the lower eyelid(s) of the affected eye(s) every 4 to 6 hours. For the first couple days, you may need to start off using Zylet every 1 to 2 hours, then use it less often as your symptoms improve.

Zylet is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also
in mycobacterial infection of the eye and fungal diseases of ocular structures.

Common side effects of Zylet:

• Eye redness
• Cornea inflammation
• Headache
• Higher eye pressure
• Eye burning and stinging

Serious side effects are rare with Zylet. Contact your healthcare provider immediately if you experience any of the following.

• High eye pressure, injury, or infection: eye pain, discomfort, or change in vision that doesn’t go away
• Allergic reaction

There are no major drug interactions listed for Zylet. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Bausch Health

It is not known if Zylet can harm your unborn baby. Talk to your healthcare provider if you are pregnant or plan to become pregnant.

• Loteprednol Etabonate/Tobramycin