XALKORI
Used for Cancer
Are you tired of high medication costs? Our service offers unbeatable savings on your XALKORI prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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XALKORI key facts
What is XALKORI?
XALKORI is the brand name for crizotinib and is available as oral capsules and pellets.
What dosages is XALKORI available in?
XALKORI is available as 200 mg and 250 mg oral capsules and 20 mg, 50 mg, and 150 mg oral pellets.
What is XALKORI used for?
XALKORI is a tyrosine kinase inhibitor that is used to treat:
- Metastatic non-small-cell lung cancer (NSCLC) with an ALK or ROS1 mutation
- Advanced anaplastic large cell lymphoma (ALCL) with an ALK mutation
- Advanced inflammatory myofibroblastic tumor (IMT) with an ALK mutation
How does XALKORI work?
XALKORI works by targeting cells that have genetic changes (mutations) in specific receptors, such as anaplastic lymphoma kinase (ALK) and ROS1. These genetic changes cause cells to become cancer cells. When XALKORI blocks the activity of these receptors, cancer cells can’t grow and spread as well.
How do I take XALKORI?
XALKORI is dosed as follows:
NSCLC
- Adults: The usual dose is 250 mg by mouth twice a day
ALCL
- Children and young adults: Your provider will determine your dose based on body surface area (BSA), which is a measurement of body size that takes into account weight and height. The usual dose ranges from 200 mg to 500 mg twice a day, depending on body size
IMT
- Adults: The usual dose is 250 mg by mouth twice a day
- Children: Your child’s provider will determine your child’s dose based on their body size, taking into account their weight and height. The usual dose ranges from 200 mg to 500 mg twice a day, depending on body size
Is it safe for me to take XALKORI?
XALKORI is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
XALKORI Common Side Effects
Common side effects of XALKORI:
- Vomiting
- Diarrhea
- Nausea
- Higher liver labs, suggesting liver irritation
- Vision changes
- Runny nose, sore throat, and other symptoms of an upper respiratory infection
- Headache
- Muscle pain
- Fever
- Swelling in the legs and feet
- Lower blood cell counts
- Mouth sores
XALKORI Serious Side Effects
Serious side effects are rare with XALKORI. Contact your healthcare provider immediately if you experience any of the following.
- Serious lung problems: sudden cough, fever, and difficulty breathing
- Heart rhythm problems: lightheadedness, blurry vision, fainting, seizures, loss of consciousness
- Serious liver problems: nausea, vomiting, tiredness, stomach pain or swelling, pale-colored stool, dark-colored urine, yellowing of the whites of the eyes or skin
Effects of other drugs, drug classes and over-the-counter products on XALKORI
The following medications may interact with XALKORI:
- Strong CYP3A Inhibitors: Avoid concomitant use
- Strong CYP3A Inducers: Avoid concomitant use
- CYP3A Substrates: Avoid concomitant use with CYP3A substrates, where minimal concentration changes may lead to serious adverse reactions
Who makes XALKORI?
Pfizer
Is XALKORI safe in pregnancy?
XALKORI can harm your unborn baby.
Females who are able to become pregnant:
- Your healthcare provider will check to see if you are pregnant before starting treatment with XALKORI.
Effective birth control (contraception) should be used during treatment with XALKORI and for 45 days after the last dose of XALKORI - Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment with XALKORI
Males who have female partners who can become pregnant:
- You should use condoms during treatment with XALKORI and for 90 days after the last dose of XALKORI
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my XALKORI prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your XALKORI prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient XALKORI savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient XALKORI savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for XALKORI | Canadian Prescription Savings* for XALKORI | XALKORI Drug Coupon* | XALKORI Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of XALKORI?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for XALKORI | Canadian Prescription Savings* for XALKORI | XALKORI Drug Coupon* | XALKORI Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the XALKORI savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the XALKORI drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for XALKORI, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the XALKORI prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, XALKORI is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed XALKORI for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the XALKORI prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the XALKORI prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for XALKORI
If you are having trouble paying for your XALKORI medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for XALKORI you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- XALKORI is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers XALKORI
- If XALKORI is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for XALKORI
If you are having trouble paying for your XALKORI medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for XALKORI you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers XALKORI
- If XALKORI is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for XALKORI
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your XALKORI treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for XALKORI you will need to meet the following criteria:
- You must be currently insured and have coverage for XALKORI
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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