Key facts about Torisel
What is Torisel?
Torisel is the brand name for temsirolimus and is available as an intravenous infusion.
What dosages is Torisel available in?
Torisel is available in a strength of 25 mg/mL.
What is Torisel used for?
Torisel is a kinase inhibitor indicated for the treatment of advanced renal cell carcinoma.
How does Torisel work?
Torisel is a kinase inhibitor which inhibits the mTOR kinase. A kinase is an enzyme that promotes cell growth. There are many types of kinases, which control different phases of cell growth. By blocking a particular enzyme from working, this medication can slow the growth of cancer cells.
How do I take Torisel?
The recommended dose of Torisel is 25 mg administered as an intravenous infusion over a 30–60 minute period once a week. Treat until disease progression or unacceptable toxicity. Pre-treatment with an antihistamine is recommended.
Is it safe for me to take Torisel?
Torisel is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Patients with bilirubin > 1.5×ULN
Torisel Common Side Effects
Common side effects of Torisel:
- Rash
- Weakness
- Nausea
- Edema
- Weight loss
- Low Red Blood Cell Count (anemia)
- High Blood Sugar (hyperglycemia)
- Increased risk of infection
Torisel Serious Side Effects
Serious side effects are rare with Torisel. Contact your healthcare provider immediately if you experience any of the following:
- Hypersensitivity/infusion reactions
- Liver damage
- Serious lung problems
- Kidney damage
- Bleeding in the brain
Effects of other drugs, drug classes and over-the-counter products on Torisel
The following medications may interact with Torisel:
- Strong inducers of CYP3A4/5 and inhibitors of CYP3A4
Who makes Torisel?
Pfizer Inc.
Is Torisel safe in pregnancy?
Torisel can cause fetal harm when administered to a pregnant woman. Females who can become pregnant should use effective contraception during treatment and for 3 months after the last dose. Males with partners who can become pregnant should use effective contraception during treatment and for 3 months after the last dose.
