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Tenex is the brand name for guanfacine and is available as an oral tablet.

Tenex is available as a 1 mg and 2 mg oral tablet.

Tenex is an alpha-2 adrenergic receptor agonist and is used to treat high blood pressure in people ages 12 years and older.

Tenex is an alpha-2 agonist. It works by binding (attaching) to alpha-2 receptors in the brain. This lowers the amount of norepinephrine, a chemical that normally raises your blood pressure by squeezing your blood vessels.

Tenex is typically dosed as 1 mg by mouth once a day at bedtime. If needed, your provider might raise your dose after 3 to 4 weeks. The maximum recommended dose is 2 mg once day.

Tenex is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have hypersensitivity to Tenex, its inactive ingredients, or other products containing guanfacine.

Common side effects of Tenex include:

• Dry mouth
• Sleepiness
• Dizziness
• Constipation
• Headache
• Weakness
• Tiredness

Serious side effects are rare with Tenex. Contact your healthcare provider immediately if you experience any of the following.

• Severely low blood pressure: lightheadedness, dizziness, feeling faint, tiredness, confusion

The following medications may interact with Tenex:

• Strong CYP3A4 inhibitors (e.g., ketoconazole): Coadministration increases the levels and effects of Tenex
• Strong CYP3A4 inducers (e.g., rifampin): Coadministration decreases the levels and effects of Tenex

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It is not known if Tenex will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.

• Guanfacine