GuanfacinePrices, Coupons & Savings
Mail Order Pharmacy
- MedicationYou saveUS ONLY
- Guanfacine HCLGeneric for TenexRx1mg30 tablets $11.4 USD30 tablets $11.4 USD - 0.38 USD/tabletSave $18.00
- Guanfacine HCl Extended Release (ER)Generic for IntunivRx2mg30 extended release tablets $6 USD30 extended release tablets $6 USD - 0.2 USD/extended release tabletSave $236.70
- Guanfacine HCl Extended Release (ER)Generic for IntunivRx3mg30 extended release tablets $6.3 USD30 extended release tablets $6.3 USD - 0.21 USD/extended release tabletSave $236.40
- Guanfacine HCl Extended Release (ER)Generic for IntunivRx4mg30 extended release tablets $6.3 USD30 extended release tablets $6.3 USD - 0.21 USD/extended release tabletSave $236.40
- Guanfacine HCl Extended Release (ER)Generic for IntunivRx1mg30 extended release tablets $5.7 USD30 extended release tablets $5.7 USD - 0.19 USD/extended release tabletSave $237.00

Do you need a prescription for guanfacine?
Yes, guanfacine is only available with a valid physician Rx.
How much is guanfacine without Insurance in the US?
Our website gives two competitive savings options to US customers who wish to purchase guanfacine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.
What will my out-of-pocket cost be for guanfacine in the US?
There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.
Is Now Patient a guanfacine savings card?
Yes. Save up to 90% on your guanfacine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.
Can you handle Rx transfers for home delivery in the US?
Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.
Is Now Patient a guanfacine coupon provider in the US?
No. Now Patient does not provide guanfacine coupons or FREE guanfacine samples.
Do you accept commercial, Medicare or Medicaid coverage for guanfacine in the US?
No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.
Does Now Patient work with Medicare?
Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.
Does Now Patient work with Commercial Insurance?
Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.
What should you do if you use too much guanfacine?
Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using guanfacine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much guanfacine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.
If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.
What should I do if I miss my dose?
There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.
Click here to find out what to do if you forgot to take your medication
What is generic guanfacine?
US brand name of guanfacine and manufacturer
Guanfacine is available under the brand name Intuniv, which is manufactured by Shire US, Inc.
UK brand name of guanfacine and manufacturer
In the UK, guanfacine is available under the brand name Intuniv.
Availability of guanfacine
Guanfacine is available by prescription only.
FDA approval of guanfacine
Guanfacine has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents.
NHS prescription (UK) for guanfacine
Guanfacine may be available in the UK with an NHS prescription, but it is important to consult with your healthcare provider or pharmacist to verify availability.
Mechanism of action
Guanfacine belongs to the class of medications known as central alpha 2A-adrenergic receptor agonists. It works by stimulating certain receptors in the brain, which leads to a reduction in sympathetic nerve activity. This helps to decrease hyperactivity and impulsivity and improve attention and behavior in individuals with ADHD. Guanfacine works in the prefrontal cortex to increase attention and cognition by activating postsynaptic norepinephrine receptors.
Uses of guanfacine
Guanfacine is primarily used for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents. Guanfacine is an effective medication for managing ADHD symptoms by targeting specific receptors in the brain, improving focus, impulse control, and hyperactivity. It is also prescribed for the treatment of hypertension (high blood pressure) and works by relaxing blood vessels and lowering blood pressure levels.
Dosage of guanfacine
The dosage of guanfacine may vary depending on the individual patient, age, and the condition being treated. It is important to follow the dosage instructions provided by your healthcare provider. The following is a general guideline for the dosages of guanfacine in the treatment of ADHD:
- Children 6 to 12 years of age: The initial recommended dose is usually 1 mg once daily. The dosage can be titrated up in increments of 1 mg per week to a maximum dosage of 4 mg per day. The dose may be gradually increased every 3 to 7 days, as determined by the healthcare provider, to achieve the desired response. The maximum recommended dose is typically 4 mg per day
- Adolescents 13 to 17 years of age: The initial recommended dose is usually 1 mg once daily. The dose may be gradually increased every 3 to 7 days, as determined by the healthcare provider, to achieve the desired response. The maximum recommended dose is typically 7 mg per day
If you miss a dose of guanfacine take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed. It is important to take guanfacine exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your doctor.
Directions
Guanfacine can be taken with or without food. However, taking it with a high-fat meal can increase absorption and may increase exposure. Guanfacine is available in two formulations: an immediate-release tablet and an extended-release tablet to take by mouth.
Is it safe to take guanfacine if I am pregnant or planning on becoming pregnant?
The safety of guanfacine in pregnancy has not been well established. If you are pregnant, planning to become pregnant or suspect you may be pregnant, it is important to discuss the use of guanfacine with your healthcare provider. They can evaluate the potential risks and benefits to determine the best course of action for your specific situation.
Is it safe to take guanfacine while breastfeeding?
Guanfacine may pass into breast milk, and its effects on infants are not well known. It is recommended to exercise caution while taking guanfacine if you are breastfeeding. Consult with your healthcare provider for guidance on the potential risks and benefits.
Warnings and precautions for guanfacine
- Guanfacine can have an impact on cardiovascular conditions, potentially causing low blood pressure and a slow heart rate. It is important for patients with pre-existing cardiovascular issues to monitor their blood pressure and heart rate regularly while taking guanfacine.
- There may be interactions between guanfacine and mental health disorders. Patients with depression or anxiety should exercise caution when taking guanfacine, as it can worsen these conditions. Close monitoring is recommended to ensure the medication does not exacerbate mental health symptoms
- Patients with liver or kidney diseases should take special consideration when using guanfacine. The dosage may need adjustment in order to prevent any adverse effects on liver or kidney function. Regular check-ups and monitoring of liver and kidney function are crucial for patients in this population
- Orthostatic hypotension may occur, particularly during initial therapy or dosage increases. Close monitoring is necessary for patients with a history of bradycardia or cardiac conduction abnormalities while taking guanfacine. Moreover, caution should be exercised as guanfacine can cause drowsiness and impair your ability to operate machinery or drive a car
- It is essential to inform your healthcare provider about all medical conditions and current medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements
Drug interactions
Guanfacine may interact with certain medications, including blood pressure medications, sedatives, and medications that affect liver enzymes. It is important to inform your healthcare provider about all the medications you are taking including supplements to avoid potential interactions. Potential drug interactions with guanfacine include:
- Antihypertensive medications: Guanfacine may enhance the blood pressure-lowering effects of other antihypertensive drugs, resulting in hypotension
- Central nervous system depressants: Combining guanfacine with sedatives or alcohol may increase drowsiness and impair coordination
Common medications that may interact with guanfacine are:
- Beta-blockers: Concurrent use of beta-blockers and guanfacine can lead to excessive bradycardia (slow heart rate)
- Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs may decrease the effectiveness of guanfacine in reducing blood pressure
Side effects of guanfacine
In clinical trials common side effects of guanfacine may include drowsiness, dry mouth, stomach pain and constipation. These are generally mild and go away on their own over time. It is important to inform your doctor if these side effects persist or worsen.
Low blood pressure, slow heart rate, and fainting spells are potentially serious side effects that may occur when taking guanfacine. These adverse reactions can significantly impact cardiovascular health and should be closely monitored by a healthcare professional. It is important to seek medical attention if any of these symptoms arise during the use of guanfacine to ensure proper management and prevention of complications.
Sources
- FDA Prescribing Information for Guanfacine
- NHS – Guanfacine
- WebMD – Guanfacine
- Drugs.com – Guanfacine
About Now Patient
Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

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