Used for Cancer

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Updated on 24 Apr 2024

talazoparib Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is talazoparib available in?

What dosages is talazoparib available in?

talazoparib is available as a 0.1 mg, 0.25 mg, 0.35 mg, 0.5 mg, 0.75 mg, and 1 mg oral capsule.

What is talazoparib used for?

What is talazoparib used for?

talazoparib is a PARP inhibitor that is used to treat:

  • Advanced or metastatic HER2-negative breast cancer with certain mutations in the BRCA gene
  • Metastatic, castration-resistant prostate cancer with HRR gene mutations; taken with Xtandi (enzalutamide)
How does talazoparib work?

How does talazoparib work?

talazoparib is a PARP inhibitor, which means it blocks the PARP protein from working. The PARP protein normally helps cells, including cancer cells, grow and survive by fixing damaged DNA. By blocking PARP from working, talazoparib prevents cancer cells from repairing their DNA, which kills the cancer cells.

How do I take talazoparib?

How do I take talazoparib?

Your dose of talazoparib depends on your cancer.

  • Breast cancer: The typical dose is 1 mg by mouth once a day
  • Prostate cancer: The typical dose is 0.5 mg by mouth once a day

Your provider might adjust your talazoparib (talazoparib) dose depending on your kidney function, any side effects you have, and the other medications you’re taking.

Is it safe for me to take talazoparib?

Is it safe for me to take talazoparib?

talazoparib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

talazoparib Common Side Effects

talazoparib Common Side Effects

Common side effects of talazoparib:

talazoparib Serious Side Effects

talazoparib Serious Side Effects

Serious side effects are rare with talazoparib.

Effects of other drugs, drug classes and over-the-counter products on talazoparib

Effects of other drugs, drug classes and over-the-counter products on talazoparib

The following medications may interact with talazoparib:

  • P-gp Inhibitors: Reduce the dose when coadministered with certain P-gp inhibitors. Monitor for increased adverse reactions
  • BCRP Inhibitors: Monitor for potential increased adverse reactions
Who makes talazoparib?

Who makes talazoparib?

Various FDA-approved generic manufacturers

Is talazoparib safe in pregnancy?

Is talazoparib safe in pregnancy?

talazoparib can harm your unborn baby, and may cause loss of pregnancy (miscarriage). You should not become pregnant during treatment with talazoparib. Tell your healthcare provider right away if you are pregnant or become pregnant during treatment with talazoparib. If you are able to become pregnant, your healthcare provider may do a pregnancy test before you start treatment with talazoparib. Females who are able to become pregnant should use effective birth control (contraception) during treatment with talazoparib and for at least 7 months after receiving the last dose of talazoparib. Talk to your healthcare provider about forms of birth control that may be right for you. Males with female partners who are pregnant or are able to become pregnant should use effective birth control during treatment with talazoparib and for at least 4 months after receiving the last dose of talazoparib.


What to do if you missed your talazoparib dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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