Key facts about Tadalafil
What dosages is Tadalafil available in?
Tadalafil is available as a 2.5 mg, 5 mg, 10 mg, and 20 mg oral tablet.
What is Tadalafil used for?
Tadalafil is a PDE-5 inhibitor used for erectile dysfunction.
How does Tadalafil work?
Tadalafil is a phosphodiesterase-5 enzyme (PDE-5) inhibitor. It works by blocking PDE-5. This is a protein in your body that breaks down the molecules that normally cause an erection. When it blocks PDE-5, Tadalafil helps an erection occur by allowing certain muscles in the penis to relax and the penis to fill with blood.
How do I take Tadalafil?
Tadalafil is typically taken by mouth about 30 minutes before sexual activity up to once per day as needed. Your provider will adjust your dose based on your response.
Is it safe for me to take Tadalafil?
Tadalafil is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you using any form of organic nitrate is contraindicated, have a history of known serious hypersensitivity reaction to Tadalafil or ADCIRCA, or are taking a guanylate cyclase (GC) stimulator such as riociguat.
Tadalafil Common Side Effects
Common side effects of Tadalafil include:
- Headache
- Runny nose, sore throat, and other symptoms of the common cold
- Indigestion
- Stomach upset
- Back pain
- Indigestion
- Back pain
Other Side Effects:
- Muscle ache
- Flushing
- Pain in arms or legs
- Diarrhea
- Dizziness
Tadalafil Serious Side Effects
Serious side effects are rare with Tadalafil. Contact your healthcare provider immediately if you experience any of the following.
- Erection lasting for more than 4 hours
- Vision loss
- Dangerously low blood pressure: feeling faint or weak, dizziness, blurry vision, feeling confused
Effects of other drugs, drug classes and over-the-counter products on Tadalafil
The following medications may interact with Tadalafil:
- Tadalafil can potentiate the hypotensive effects of nitrates, alphablockers, antihypertensives or alcohol.
- CYP3A4 inhibitors (e.g. ketoconazole, ritonavir) can increase Tadalafil exposure requiring dose adjustment.In this situation the dose should be no more than 10 mg every 72 hours and Tadalafil for once daily use: dose not to exceed 2.5 mg.
- CYP3A4 inducers (e.g. rifampin) decrease Tadalafil exposure requiring dose adjustment.
Who makes Tadalafil?
Various FDA-approved generic manufacturers
Is Tadalafil safe in pregnancy?
Tadalafil is not indicated for use in females.













