SYMLIN

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Manufactured by AstraZeneca

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SYMLIN Uses, Side Effects, Interactions, Warnings & Dosing

What is SYMLIN?

What is SYMLIN?

SYMLIN is the brand name for pramlintide and is available as a subcutaneous injection.

What dosages is SYMLIN available in?

What dosages is SYMLIN available in?

SYMLIN is available as a:

  • 1.5 mL SymlinPen 60 disposable multidose pen-injector, (1000 mcg/mL) for 15, 30, 45, and 60 mcg doses
  • 2.7 mL SymlinPen 120 disposable multidose pen-injector, (1000 mcg/mL) for 60 and 120 mcg doses
What is SYMLIN used for?

What is SYMLIN used for?

SYMLIN is an amylin analog that is used to treat:

  • Type 1 diabetes
  • Type 2 diabetes
How does SYMLIN work?

How does SYMLIN work?

SYMLIN is an amylin analog. It’s a man-made version of human amylin. Amylin helps lower blood sugar in three ways: making you feel full after meals, lowering the amount of sugars released by your body, and lowering the amount of calories your body absorbs.

How do I take SYMLIN?

How do I take SYMLIN?

SYMLIN is typically dosed as follows:

  • Type 1 diabetes: The medication starts at 15 mcg injected subcutaneously (under the skin) before major meals. If you don’t feel nauseous after three days, the dose is raised (usually around 30 mcg to 60 mcg before major meals)
  • Type 2 diabetes: The medication starts at 60 mcg injected subcutaneously (under the skin) before major meals. If you don’t feel nauseous after three days, the dose is raised to 120 mcg before major meals
Is it safe for me to take SYMLIN?

Is it safe for me to take SYMLIN?

SYMLIN is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

  • Prior serious hypersensitivity reaction to SYMLIN or its ingredients
  • Hypoglycemia unawareness
  • Confirmed gastroparesis
SYMLIN Common Side Effects

SYMLIN Common Side Effects

Common side effects of SYMLIN:

  • Nausea
  • Loss of appetite
  • Headache
  • Vomiting
  • Tiredness
  • Joint pain
  • Dizziness
SYMLIN Serious Side Effects

SYMLIN Serious Side Effects

Serious side effects are rare with SYMLIN. Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions
Effects of other drugs, drug classes and over-the-counter products on SYMLIN

Effects of other drugs, drug classes and over-the-counter products on SYMLIN

The following medications may interact with SYMLIN:

  • Insulin: SYMLIN and insulin must not be mixed and must be administered as separate injections
  • Oral Medications: SYMLIN has the potential to delay the absorption of concomitantly administered oral medications. Oral medications should be administered at least 1 hour prior to SYMLIN injection or 2 hours after SYMLIN injection
  • Drugs Affecting Gastrointestinal Motility: Due to its effects on gastric emptying, SYMLIN should not be considered for patients taking medications that alter gastrointestinal motility (e.g., anticholinergic agents such as atropine) or medications that slow the intestinal absorption of nutrients (e.g., alpha-glucosidase inhibitors).

Drugs Affecting Glucose Metabolism:

  • The following are examples of medications that may increase the susceptibility to hypoglycemiawhen administered with SYMLIN: oral anti-diabetic products, angiotensin converting enzyme
  • (ACE) inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors pentoxifylline, propoxyphene, salicylates, somatostatin analogs, and sulfonamide antibiotics
  • SYMLIN and these drugs should be coadministered with caution
Who makes SYMLIN?

Who makes SYMLIN?

AstraZeneca

Is SYMLIN safe in pregnancy?

Is SYMLIN safe in pregnancy?

It is not known if SYMLIN will harm your unborn baby. You and your healthcare provider should decide how to best control your blood sugar levels during pregnancy.

What is the generic name for SYMLIN?

What is the generic name for SYMLIN?

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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