Used for Psoriasis

View SPEVIGO savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or SPEVIGO Patient Assistance Program.

Programs are suitable for individuals who want to buy SPEVIGO without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Boehringer Ingelheim Pharmaceuticals, Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

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    Rx Advantage Card

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    Save up to 90%

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    Canadian Prescription Savings

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  • Unavailable

    Drug Coupons

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  • Available

    Patient Assistance Programs

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about SPEVIGO

What is SPEVIGO?

What is SPEVIGO?

SPEVIGO is the brand name for spesolimab-sbzo and is available as an injection for IV use.

What dosages is SPEVIGO available in?

What dosages is SPEVIGO available in?

SPEVIGO is available as a 450 mg/7.5 mL (60 mg/mL) solution for IV use.

What is SPEVIGO used for?

What is SPEVIGO used for?

SPEVIGO is a monoclonal antibody and is used for treatment of generalized pustular psoriasis flares.

How does SPEVIGO work?

How does SPEVIGO work?

SPEVIGO is a monoclonal antibody. It works by blocking the interleukin-36 receptor (IL-36R), which is normally a key part of your immune system’s signaling pathway. Blocking this pathway can help manage GPP flares caused by IL-36 (inflammatory proteins).

How do I take SPEVIGO?

How do I take SPEVIGO?

SPEVIGO is typically dosed as 900 mg injected as a single dose into your veins over 90 minutes. If your GPP flare symptoms don’t go away, your provider might give you an additional 900 mg dose (over 90 minutes) one week after the first dose.

Is it safe for me to take SPEVIGO?

Is it safe for me to take SPEVIGO?

SPEVIGO is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

SPEVIGO Common Side Effects

SPEVIGO Common Side Effects

Common side effects of SPEVIGO:

  • Weakness and feeling tired
  • Nausea and vomiting
  • Headache
  • Itchy skin
  • Bruising around the infusion site
  • Urinary tract infection
SPEVIGO Serious Side Effects

SPEVIGO Serious Side Effects

Serious side effects are rare with SPEVIGO. Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: trouble breathing; fever; hives; blisters; swelling of the lips, throat, tongue, or face
Effects of other drugs, drug classes and over-the-counter products on SPEVIGO

Effects of other drugs, drug classes and over-the-counter products on SPEVIGO

There are no major drug interactions listed for SPEVIGO. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes SPEVIGO?

Who makes SPEVIGO?

Boehringer Ingelheim Pharmaceuticals, Inc.

Is SPEVIGO safe in pregnancy?

Is SPEVIGO safe in pregnancy?

It is not known if SPEVIGO may harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.


What to do if you missed your SPEVIGO dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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