spesolimab-sbzo
Used for Psoriasis
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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spesolimab-sbzo Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is spesolimab-sbzo available in?
spesolimab-sbzo is available as a 450 mg/7.5 mL (60 mg/mL) solution for IV use.
What is spesolimab-sbzo used for?
spesolimab-sbzo is a monoclonal antibody and is used for treatment of generalized pustular psoriasis flares.
How does spesolimab-sbzo work?
spesolimab-sbzo is a monoclonal antibody. It works by blocking the interleukin-36 receptor (IL-36R), which is normally a key part of your immune system’s signaling pathway. Blocking this pathway can help manage GPP flares caused by IL-36 (inflammatory proteins).
How do I take spesolimab-sbzo?
spesolimab-sbzo is typically dosed as 900 mg injected as a single dose into your veins over 90 minutes. If your GPP flare symptoms don’t go away, your provider might give you an additional 900 mg dose (over 90 minutes) one week after the first dose.
Is it safe for me to take spesolimab-sbzo?
spesolimab-sbzo is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
spesolimab-sbzo Common Side Effects
Common side effects of spesolimab-sbzo:
- Weakness and feeling tired
- Nausea and vomiting
- Headache
- Itchy skin
- Bruising around the infusion site
- Urinary tract infection
spesolimab-sbzo Serious Side Effects
Serious side effects are rare with spesolimab-sbzo. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: trouble breathing; fever; hives; blisters; swelling of the lips, throat, tongue, or face
Effects of other drugs, drug classes and over-the-counter products on spesolimab-sbzo
There are no major drug interactions listed for spesolimab-sbzo. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes spesolimab-sbzo?
Various FDA-approved generic manufacturers
Is spesolimab-sbzo safe in pregnancy?
It is not known if spesolimab-sbzo may harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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