SINEMET ®
Coupons, Savings & Patient Assistance
Learn more about SINEMET® and see what savings options may be available to you that can help bring down the cost of your medication.
Options may include Rx Advantage Card, Copay assistance & Coupons, or Patient Assistance Programs. Suitable for insured, underinsured or uninsured individuals. Pay as little as $0 per fill.
Manufactured by Merck & Co., Inc..
This content is intended for US audiences only
Drug savings programs
- Qualified
Good News! You can save up to 90% on the cost of your SINEMET® when using the FREE NowPatient’s Rx Advantage Card at your local pharmacy.
- AvailableN/AManufactured byN/A
- Unavailable
Unfortunately, Merck & Co., Inc. who manufactures SINEMET®, does not offer a co-pay assistance program at this time. Please check back regularly as this situation may change.
Option Not Available - Unavailable
Unfortunately, Merck & Co., Inc. who manufactures SINEMET®, does not offer a patient assistance program at this time. Please check back regularly as this situation may change.
Option Not Available
Learn more about SINEMET
What is SINEMET?
SINEMET is the brand name for carbidopa/levadopa and is available as an oral tablet.
What dosages is SINEMET available in?
SINEMET is available as a 10 mg/100 mg, 25 mg/100 mg, and 25 mg/250 mg oral tablet.
What is SINEMET used for?
SINEMET is a dopa decarboxylase inhibitor / dopamine replacement and is used to treat the following:
- Parkinson’s disease (PD)
- Parkinsonism (conditions that cause people to have signs and symptoms of PD, including slowness, stiffness, shakiness, and imbalance)
How does SINEMET work?
SINEMET is a combination of two medications: carbidopa and levodopa. By working together, these medications help relieve symptoms of Parkinson’s disease (PD), which occur due to low dopamine levels in the brain. Levodopa is a dopamine replacement. Levodopa travels into your brain, where it’s converted into dopamine. It helps relieve PD symptoms by restoring dopamine in your brain. Carbidopa is a dopa decarboxylase inhibitor. Dopa decarboxylase is a protein in your body that breaks down levodopa before it can travel into your brain.
By blocking this protein, carbidopa prevents levodopa from breaking down. This raises the level of levodopa in your body and allows more levodopa to travel into your brain to be converted into dopamine. Levodopa and dopamine can then reach and remain at higher levels in your brain, which enhances levodopa’s ability to relieve PD symptoms.
How do I take SINEMET?
SINEMET is typically started at 25 mg/100 mg (carbidopa/levodopa) by mouth 3 times per day. Your healthcare provider will slowly raise your dose until your symptoms of PD are relieved.
Is it safe for me to take SINEMET?
SINEMET is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with SINEMET. These inhibitors must be discontinued at least two weeks prior to initiating therapy with SINEMET.
SINEMET Common Side Effects
Common side effects of SINEMET:
- Involuntary movements
- Nausea
SINEMET Serious Side Effects
Serious side effects are rare with SINEMET. Contact your healthcare provider immediately if you experience any of the following.
- Neuroleptic malignant syndrome (NMS): very high fevers, confusion, irregular pulse, sweating, muscle stiffness, changes in blood pressure
Effects of other drugs, drug classes and over-the-counter products on SINEMET
The following medications may interact with SINEMET:
- Symptomatic postural hypotension has occurred when carbidopa levodopa preparations were added to
- the treatment of patients receiving some antihypertensive drugs
- Concomitant therapy with selegiline and carbidopa levodopa may be associated with severe orthostatic hypotension not attributable to carbidopa levodopa alone
- There have been rare reports of adverse reactions, including hypertension and dyskinesia, resulting from the concomitant use of tricyclic antidepressants and carbidopa levodopa preparations
- Dopamine D2 receptor antagonists (e.g., phenothiazines, butyrophenones, risperidone) and isoniazid may reduce the therapeutic effects of levodopa. In addition, the beneficial effects of levodopa in Parkinson’s disease have been reported to be reversed by phenytoin and papaverine. Patients taking these drugs with SINEMET should be carefully observed for loss of therapeutic response
- Use of SINEMET with dopamine-depleting agents (e.g., reserpine and tetrabenazine) or other drugs known to deplete monoamine stores is not recommended
- SINEMET and iron salts or multivitamins containing iron salts should be coadministered with caution. Iron salts can form chelates with levodopa and carbidopa and consequently reduce the bioavailability of carbidopa and levodopa
Who makes SINEMET?
Merck & Co., Inc.
Is SINEMET safe in pregnancy?
There are no adequate and well-controlled studies in pregnant women and SINEMET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
What to do if you missed your SINEMET ® dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsWhat can I do if I am commercially insured but cannot afford my SINEMET ®?
If you are commercially insured and you cannot afford your SINEMET® copay or co-insurance you have four options:
Option
Savings Information
Copay Assistance Program
Check at the top of the page to see if there is a SINEMET® Copay Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your SINEMET® for as little as $0 per fill.
Patient Assistance Program
Check at the top of the page to see if there is a SINEMET® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your SINEMET® for no cost.
Rx Advantage Card
You can use the NowPatient Rx Advantage Card which removes the constraints of insurance and the cost can be typically lower than your plan copay or co-insurance. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.
Medicaid
If the above options are not feasible then you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
What can I do if I am uninsured and cannot afford my SINEMET ®?
If you are uninsured and you cannot afford your SINEMET®, then you have three options:
Option
Savings Information
Patient Assistance Program
Check at the top of the page to see if there is a SINEMET® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your SINEMET® for no cost.
Rx Advantage Card
You can use the NowPatient Rx Advantage Card at a local pharmacy and obtain prices that are typically 80% of standard retail prices.
Medicaid
If the above options are not feasible then you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
What can I do if I am insured with Medicare and cannot afford my SINEMET ®?
If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have four options:
Option
Savings Information
Patient Assistance Program
Check at the top of the page to see if there is a SINEMET® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your SINEMET® for no cost.
Rx Advantage Card
You can use the NowPatient Rx Advantage Card which removes the constraints of insurance and the cost can be typically lower than your plan copay or co-insurance. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.
Low Income Subsidy
If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
Medicaid
The final option is to check ‘dual eligibility’ to Medicaid in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
Am I eligible for the Rx Advantage Card and how much does SINEMET ® cost without insurance?
Our website gives savings options to customers who wish to purchase SINEMET®, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.
What will my out-of-pocket cost be for SINEMET ® when using the Rx Advantage Card?
Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for SINEMET® using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.
Is it legal for me to pay cash for SINEMET ® even though I have insurance?
Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.
Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?
No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket SINEMET® cash price you pay can be typically cheaper than your plan copay.
Does the Rx Advantage Card work with Commercial Insurance?
We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket SINEMET® cash price you pay can be typically cheaper than your plan copay.
How do I check prices for SINEMET ® and how do I use the Rx Advantage Card?
You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your SINEMET® Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.
Do I need to pay for the Rx Advantage Card?
No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.
Is there a SINEMET ® co-pay program?
You can check the top of the page to see if there is an option for a SINEMET® co-pay card. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.
What are the eligibility requirements for a SINEMET ® co-pay card and how much do I have to pay?
Eligibility requirements vary between pharmaceutical companies. However, they almost all require you to be commercially insured. If you qualify there is no cost to you. It is a FREE program.
Can I enroll in the SINEMET ® co-pay program if I have state, federal, or other government insurance?
Most likely, no. The copay card program is primarily designed for commercially or privately insured individuals. However, if you are finding it difficult to afford your medication, then there are other forms of assistance. For example, you can apply for LIS (Low Income Subsidy) or extra help is available online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778). As well, you can look at state assistance programs like Medicaid.
Can I enroll in the SINEMET ® co-pay program if I have no insurance?
Most likely No. However, many pharmaceutical companies offer fully funded free programs for uninsured persons. These programs are called Patient Assistance Programs (PAP) and NowPatient provides a useful resource to check program availability and eligibility.
How can I check if I am eligible for the SINEMET ® co-pay program?
If a SINEMET® co-pay card exists, you will see it as a savings option at the top of the page. You can select the option and it will direct you to an eligibility checker. If you qualify you will be prompted to create an account with NowPatient, from where you will be able to access the instructions on how to enroll.
How do I use the SINEMET ® co-pay card?
Once you are enrolled into the program you will be able to download the card. When you next fill your Rx, simply present the co-pay card to the pharmacist. The Pharmacist will use the card to process and submit your claim. You will then be provided with your discount. The program cost is covered by the pharmaceutical company.
Is there a SINEMET ® Patient Assistance Program (PAP)?
You can check the top of the page to see if there is an option for a SINEMET patient assistance program. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.
What are the eligibility requirements for a SINEMET ® PAP and how much do I have to pay?
Eligibility requirements vary between pharmaceutical companies. However, they almost all require you to be uninsured, underinsured with no drug coverage, or insured but unable to afford your co-pay or co-insurance contribution. If you qualify there is no cost to you. It is a FREE program funded by the pharmaceutical company.
Can I enroll in a SINEMET ® PAP if I have state, federal, or other government insurance?
It is possible. Some programs do not allow any insured individuals to apply, however, some programs do have exceptions. If you find that you do not qualify and are finding it difficult to afford your medication, then there are other forms of assistance. For example, you can apply for LIS (Low Income Subsidy) or extra help is available online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778). As well, you can look at state assistance programs like Medicaid.
Can I enroll in a SINEMET ® PAP if I have no insurance?
Yes. Most programs are open to individuals who are uninsured and meet income eligibility criteria.
How can I check if I am eligible for the SINEMET ® PAP?
If a SINEMET® patient assistance program exists, you will see it as a savings option at the top of the page. You can select the option and it will direct you to an eligibility checker. If you qualify you will be prompted to create an account with NowPatient, from where you will be able to access the instructions on how to enroll.
How do I use the SINEMET ® PAP to obtain my medication?
Once you are enrolled in the program you will be advised by the pharmaceutical company how they will make supplies to you. In most cases, they will ship the medication through their nominated mail-order pharmacy, directly to you. However, depending on the nature of the medication, the pharmaceutical company may opt to provide you with a pharmacy card (which you can redeem against your medication for FREE at your nearby pharmacy) or ship the medication directly to your healthcare provider (HCP).
Refills are usually handled by the pharmaceutical company.
I am insured but I do not qualify for patient assistance or copay assistance for SINEMET ®. Is there any other form of assistance that can help with the costs of my existing copays or co-insurance?
There are a number of resources available such as charitable foundations that may be able to provide assistance for your SINEMET®:
Patient Access Network Foundation (PAN) assistance for SINEMET®
If you are having trouble paying for your SINEMET® medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for SINEMET® you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- SINEMET® is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers SINEMET®
- If SINEMET® is listed on PAN's list of covered medications
You can check the Patient Access Network Foundation Website for more information.
HealthWell Foundation Copay Program for SINEMET®
If you are having trouble paying for your SINEMET® medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for SINEMET® you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers SINEMET®
- If SINEMET® is listed on the HealthWell Foundation's list of covered medications
You can check the HealthWell Foundation Website for more information.
Patient Advocate Foundation Co-Pay Relief Program for SINEMET®
Patient Advocate Foundation's Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your SINEMET® treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for SINEMET® you will need to meet the following criteria:
- You must be currently insured and have coverage for SINEMET®
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 3000r 4000f the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Can I buy my SINEMET ® from Canada?
Americans pay at least twice as much (in fact 218%) on prescription medications than individuals in other countries, like Canada. The reason why Canada drugs are cheaper is that Canada regulates its prescription medication drug prices (the Patented Medicines Prices Review Board) meaning that consumers pay less for their SINEMET®. This prevents pharmaceutical patentees from charging excessive prices.
As well, many Canadian drugs are likely produced by exactly the same companies in the same factories, as US prescription drugs.
We have partnered with Prescription Help in Canada that carries thousands of branded and generic medications. If there is an option for SINEMET® from Canada, then we will provide this as an Rx savings option to you.
Is it safe for me to buy my SINEMET ® from Prescription Help, Canada?
If you purchase SINEMET® from Canadian Prescription Help, then there is little reason to worry about safety since it is likely that the drugs will be the same ones you would get from your American drugstore, and would have undergone the same rigorous testing as the American counterparts. Canada drugs are regulated for safety, efficacy and quality by Health Canada, which is the Canadian equivalent of the Food and Drug Administration (FDA). If you are unsure, you can discuss this option with your physician, especially if you find it difficult affording your medications and may therefore risk not being treated.
Rest assured, NowPatient has done thorough due diligence on Prescription Help, to ensure that the service is adequately licensed, regulated and safe.
We have checked and verified that Prescription Help:
- Is a licensed pharmacy in Canada.
- Will only fill your SINEMET® if you have a valid prescription.
- Has a licensed pharmacist on staff to answer your questions.
- Does not send medicine that looks different than what you receive at your usual drug store, nor does it arrive in packaging that is damaged, in a foreign language, has no expiration date, or is expired.
- Does not charge you for products that you never ordered or received.
- Provides clear written protections for your personal and financial information, including credit card numbers.
- Maintains the highest standards of data security and compliance.
- Does not sell your information to other websites.
- Does not supply controlled substances.
- Does not supply any products on an FDA Import Alert.
- Quantities are restricted to a maximum of 3 month's supply for international orders.
- Publishes contact information on website for customer service.
Is ordering SINEMET ® from a Canadian Pharmacy legal?
Although it is technically not legal for individuals to import prescription drugs, It is notable that U.S. government officials have stated that individuals who procure non-controlled prescription drugs from Canada or other foreign sources for up to a three-month supply for their own use are not pursued or prosecuted. There are hundreds of thousands of American patients who have used or continue to use Canadian pharmacies to procure their medications at significant discounts. Often the price of medications can be the difference between getting treated or not being treated.
How do I place an order for SINEMET ® from Prescription Help, Canada?
If your medication is available from our partner Canadian Pharmacy, then we will show it as an option. You can search for the product by pack size, strength or form and then see the price for SINEMET®. If you are happy with the price, you can proceed to the checkout. This will take you to the Prescription Help website, from where you can complete the process. Prescription Help is not connected to NowPatient other than as an affiliate partner which offers services that may benefit NowPatient users. It is not insurance, any payments are strictly cash and are considered out-of-pocket.
What should I do if I take too much SINEMET ®?
Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using SINEMET®. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much SINEMET®. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Important Information
What exactly does Sinemet do?
Should Sinemet be taken at bedtime?
Does Sinemet stop tremors?
What side effects does Sinemet have?
Does Sinemet help with walking?
What should I eat when taking Sinemet?
Is Sinemet a sedative?
What worsens Parkinson's disease?
Why was Sinemet discontinued?
Can Sinemet be stopped abruptly?
Has Sinemet been discontinued?
How long can you be on Sinemet?
What is the most prominent side effect of Sinemet 25 100 mg?
Why is it important to take Sinemet on time?
Why is Sinemet better than levodopa?
How long does Sinemet work for Parkinson's?
What is the difference between carbidopa-levodopa and Sinemet?
Is Sinemet better than generic?
Is Sinemet used for dementia?
What is the difference between Sinemet and half Sinemet?
Does Sinemet replace dopamine?
What to avoid when taking Sinemet?
What is the best food to take with Sinemet?
What vitamins should not be taken with carbidopa levodopa?
What drugs Cannot be taken with levodopa?
Does food interfere with Sinemet?
Can you drink coffee with carbidopa levodopa?
What is the best breakfast for Parkinson's patients?
Are bananas good for Parkinson's?
What is the best time of day to take carbidopa levodopa?
What foods help with dopamine in Parkinson's?
When is the best time to take Sinemet?
Should you take Sinemet at bedtime?
How long do you have to wait to take Sinemet after eating?
How many days does it take for Sinemet to start working?
What time of day are Parkinson's symptoms worse?
Does Sinemet interfere with sleep?
Is sleep a side effect of Sinemet?
Should you take carbidopa levodopa before bed?
Does Sinemet work immediately?
Can you take Sinemet 25 100 three times a day?
What is the most common adverse reaction to Sinemet?
What are the signs of too much carbidopa-levodopa?
How many hours does Sinemet last?
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