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MEDICAL INFORMATION
Rozerem Key Facts
What is Rozerem?
Rozerem is the brand name for ramelteon and is available as an oral tablet.
What dosages is Rozerem available in?
Rozerem is available as an 8 mg oral tablet.
What is Rozerem used for?
Rozerem is a melatonin receptor agonist and is used to treat insomnia.
How does Rozerem work?
Rozerem is a melatonin receptor agonist which means that it acts like melatonin. Melatonin is a natural hormone that your body makes when it is dark to help maintain a normal sleeping cycle. By working like melatonin, Rozerem helps you fall asleep faster.
How do I take Rozerem?
Rozerem is dosed as 8 mg by mouth within 30 minutes before bedtime. Take it on an empty stomach. Don’t take more than 8 mg of Rozerem a day.
Is it safe for me to take Rozerem?
Rozerem is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you any of the following apply:
- History of angioedema while taking Rozerem
- Are taking fluvoxamine (strong CYP1A2 inhibitor):
- Increases AUC for ramelteon and should not be used in combination
Rozerem Common Side Effects
Common side effects of Rozerem:
- Dizziness
- Sleepiness
- Fatigue
- Nausea
- Worsening insomnia
Rozerem Serious Side Effects
Serious side effects are rare with Rozerem. Contact your healthcare provider immediately if you experience any of the following.
- Angioedema: swelling of your face, lips, tongue, or throat
Suicidal thoughts or behaviors
Effects of other drugs, drug classes and over-the-counter products on Rozerem
The following medications may interact with Rozerem:
- Rifampin (strong CYP enzyme inducer): Decreases exposure to and effects of ramelteon
- Ketoconazole (strong CYP3A4 inhibitor): Increases AUC for ramelteon; administer with caution
- Fluconazole (strong CYP2C9 inhibitor): Increases systemic exposure of ramelteon; administer with caution
- Donepezil: Increases systemic exposure of ramelteon; patients should be closely monitored when ramelteon is coadministered with donepezil
- Doxepin: Increases systemic exposure of ramelteon; patients should be closely monitored when ramelteon is coadministered with doxepin
- Alcohol: Causes additive psychomotor impairment; should not be used in combination
Who makes Rozerem?
Takeda Pharmaceuticals
Is Rozerem safe in pregnancy?
It is not known if Rozerem can harm an unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
What is the generic name for Rozerem?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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