rituximab-arrx
Used for Cancer
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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rituximab-arrx Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is rituximab-arrx available in?
rituximab-arrx is available as a 100 mg/10 mL (10 mg/mL) and 500 mg/50 mL (10mg/mL) solution in single-dose vials.
What is rituximab-arrx used for?
rituximab-arrx is an anti-CD20 monoclonal antibody and is used for the following:
Blood cancers:
- Certain types of CD20-positive non-Hodgkin’s lymphoma (NHL) in adults and children ages 6 months and older
- CD20-positive chronic lymphocytic leukemia (CLL) in adults
Autoimmune conditions:
- Moderate to severe rheumatoid arthritis (RA) in adults
Granulomatosis with polyangitis (GPA) and microscopic polyangitis (MPA) in adults and children ages 2 years and older
Moderate to severe pemphigus vulgaris in adults
How does rituximab-arrx work?
rituximab-arrx is a monoclonal antibody. It targets specific immune cells called B cells that can be involved in a range of different health conditions. For example, B cells sometimes turn into cancer cells. Other times, they become overly active and cause autoimmune conditions. rituximab-arrx works by attaching a specific protein on the B cells called CD20. When it does so, it signals to the body to attack and kill that cell. As a result, these abnormal or overly active B cells can’t grow, spread, or work as well.
How do I take rituximab-arrx?
rituximab-arrx is dosed as follows:
- Your provider will determine your dose of rituximab-arrx based on your body surface area (BSA) in m². This medication is typically given by a healthcare provider in a hospital or infusion clinic setting. Your provider might also give you other anticancer medications along with rituximab-arrx
Is it safe for me to take rituximab-arrx?
rituximab-arrx is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
rituximab-arrx Common Side Effects
Common side effects of rituximab-arrx:
- Fever
- Lower white blood cell counts
- Chills
- Infection
- Weakness
- Nausea
- Headache
- Night sweats
- Rash
rituximab-arrx Serious Side Effects
Serious side effects are rare with rituximab-arrx. Contact your healthcare provider immediately if you experience any of the following.
- Infusion-related reaction: swelling, trouble breathing, chest pain, low blood pressure, red skin
- Serious skin reaction: painful blisters, skin wounds, peeling skin, fever, sore throat, body aches
- Tears in the gut: sudden and severe stomach pain, fever, chills, and nausea or vomiting that won’t go away
- Infection: fever, chills, cough, muscle aches, very fast heartbeat, severe tiredness
- Tumor lysis syndrome: seizures, hallucinations, nausea, tiredness, no appetite, dark-colored urine, muscle cramps, numbness
- Serious heart problems: tiredness, weakness, dizziness, feeling faint, trouble breathing, pressure on the chest, pounding heart, irregular heart beat, sweating, feeling anxious, nausea
Effects of other drugs, drug classes and over-the-counter products on rituximab-arrx
The following medications may interact with rituximab-arrx:
- Renal toxicity when used in combination with cisplatin
Who makes rituximab-arrx?
Various FDA-approved generic manufacturers
Is rituximab-arrx safe in pregnancy?
Talk to your healthcare provider about the risks to your unborn baby if you receive rituximab-arrx during pregnancy.
Females who are able to become pregnant:
- Your healthcare provider should do a pregnancy test to see if you are pregnant before starting rituximab-arrx
- You should use effective birth control (contraception) during treatment with rituximab-arrx and for 12 months
after your last dose of rituximab-arrx. Talk to your healthcare provider about effective birth control - Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with rituximab-arrx
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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