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Prednisone is available as a 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, and 50 mg oral tablet as well as a 5 mg/5 ml oral solution.

Prednisone is a corticosteroid and is used to treat allergies or allergic reactions, skin conditions, conditions affecting certain hormones (e.g., low adrenal hormones), eye conditions, lung conditions, gut conditions (e.g., ulcerative colitis), conditions related to blood cells, certain cancers (e.g., leukemia), nervous system conditions (e.g., multiple sclerosis), joint conditions (e.g., rheumatoid arthritis), and lupus.

Prednisone is a corticosteroid. It’s a lab-made medication that’s similar to cortisol, a natural stress hormone your body makes. Prednisone works by calming down your body’s immune response that otherwise would cause you pain and discomfort (e.g., itching, redness, swelling).

Prednisone is typically taken by mouth and the dose ranges from 5 mg to 60 mg by mouth per day, depending on the condition being treated.

Prednisone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have a systemic fungal infection.

Common side effects of Prednisone include:

• Swelling (e.g., puffiness in the face, hands, or feet)
• Stomach bloating
• Muscle weakness
• Headache
• Insomnia (trouble sleeping)
• Changes in your mood
• Larger appetite (possibly leading to weight gain)
• Higher blood sugar

Serious side effects are rare with Prednisone. Contact your healthcare provider immediately if you experience any of the following.

• Serious allergic reaction: trouble breathing or swallowing; swelling (on your face, lips, mouth, or throat); peeling skin; rash; hives

The following medications may interact with Prednisone:

• Phenytoin, phenobarbital, ephedrine, and rifampin – May decrease the levels and effects of Prednisone
• Warfarin – May alter PT time
• Potassium depleting diuretics – May increase risk of hypokalemia

Various FDA-approved generic manufacturers

It is not known if Prednisone will harm your unborn baby. If you become pregnant while receiving Prednisone, talk to your healthcare provider. Infants born of mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism.

• Deltasone