PantoprazolePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Pantoprazole Delayed Release (DR)
    Generic for Protonix
    30 delayed release tablets $4.2 USD
    Save $67.20
  3. Pantoprazole Delayed Release (DR)
    Generic for Protonix
    30 delayed release tablets $4.5 USD
    Save $66.90
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Do you need a prescription for pantoprazole?

Yes, pantoprazole is only available with a valid physician Rx.

How much is pantoprazole without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase pantoprazole, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for pantoprazole in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a pantoprazole savings card?

Yes. Save up to 90% on your pantoprazole with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a pantoprazole coupon provider in the US?

No. Now Patient does not provide pantoprazole coupons or FREE pantoprazole samples.

Do you accept commercial, Medicare or Medicaid coverage for pantoprazole in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much pantoprazole?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using pantoprazole. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much pantoprazole. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand Name of pantoprazole and manufacturer

Pantoprazole is available in the US under the brand name Protonix. It is manufactured by Pfizer Inc.

UK brand Name of pantoprazole and manufacturer

Pantoprazole is available in the UK as a generic.  It is manufactured by multiple generic manufacturers.

Is pantoprazole available in the UK on the NHS?

Yes, pantoprazole is available in the UK on the NHS as a prescription medication.

Prescription requirement for pantoprazole

Pantoprazole is a prescription medication and requires a prescription from a healthcare provider.

FDA approval of pantoprazole

Pantoprazole has received FDA approval for the treatment of certain gastrointestinal conditions, including gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome.

Active ingredient of pantoprazole and mechanism of action

The active ingredient in pantoprazole is pantoprazole sodium. It belongs to a class of medications known as proton pump inhibitors (PPIs). Pantoprazole works by reducing the production of stomach acid. It specifically inhibits the enzyme H+/K+-ATPase in the gastric parietal cells, which leads to a decrease in gastric acid secretion.

Uses of pantoprazole

Pantoprazole is primarily used for the treatment of gastrointestinal conditions, including:

It may also be used in combination with antibiotics for the treatment of Helicobacter pylori (H. pylori) infection.

Forms of pantoprazole

Pantoprazole is available in various forms, including oral tablets and oral suspension. The specific form and strength will depend on the intended use and the formulation of the medication.

Dosage of pantoprazole

The dosage of pantoprazole will vary depending on the specific condition being treated, the severity of symptoms, and individual patient factors. It is important to follow the dosage instructions provided by your healthcare provider. If you forget to take a dose of pantoprazole, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at your normal time.  Typically, the recommended adult dose for GERD is 40 mg once daily for up to 8 weeks. Take pantoprazole an hour before a meal, and swallow the tablets whole with a drink of water. You may take antacids with pantoprazole.

Precautions and warnings for pantoprazole

  • Pantoprazole may increase the risk of certain infections, such as pneumonia and gastrointestinal infections. It is important to follow proper hygiene practices and consult with your healthcare provider if you experience symptoms of infection
  • Inform a healthcare professional about any liver problems or other medical conditions you have, as pantoprazole may affect liver function
  • Pantoprazole may interact with other medications, so it is important to inform your healthcare provider about all the medications you are taking
  • Long-term use of pantoprazole may be associated with an increased risk of certain side effects, such as bone fractures and vitamin B12 deficiency. Discuss with your healthcare provider the potential benefits and risks of long-term use
  • Let your doctor know if you have low blood levels of magnesium, calcium, or potassium, before starting treatment
  • Pantoprazole passes into breast milk. Speak to your doctor before breast-feeding

Side effects of pantoprazole

Common side effects of pantoprazole may include:

  • Headache
  • Diarrhea
  • Nausea
  • Stomach pain
  • Flatulence
  • Dizziness
  • Joint pain

Allergic reactions to this drug are rare. Contact your healthcare provider if you experience any persistent or serious side effects.

Interactions with other drugs

Pantoprazole may interact with certain prescription drugs, including methotrexate, atazanavir, erlotinib, nelfinavir, rilpivirine, warfarin, digoxin, antifungals such as ketoconazole, and drugs that affect the liver enzymes responsible for the metabolism of pantoprazole. It is important to inform your healthcare provider about all the medications you are taking including over-the-counter, vitamins and supplements, to avoid potential drug interactions.

Similar drugs to pantoprazole

Dexlansoprazole, esomeprazole, lansoprazole, omeprazole.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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