Used for Depression

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

PAMELOR Uses, Side Effects, Interactions, Warnings & Dosing

What is PAMELOR?

What is PAMELOR?

PAMELOR is the brand name for nortriptyline and is available as an oral capsule and solution.

What dosages is PAMELOR available in?

What dosages is PAMELOR available in?

PAMELOR is available as a 10 mg, 25 mg, 50 mg, and 75 mg oral capsule and a 10 mg/5 ml oral solution.

What is PAMELOR used for?

What is PAMELOR used for?

PAMELOR is a tricyclic antidepressant that is used to treat depression.

How does PAMELOR work?

How does PAMELOR work?

PAMELOR is a tricyclic antidepressant (TCA). It helps improve your mood by adjusting the levels of serotonin, norepinephrine, and other similar chemicals in your brain.

How do I take PAMELOR?

How do I take PAMELOR?

PAMELOR is typically dosed at 25 mg by mouth three or four times daily. Doses above 150 mg per day are not recommended.

Is it safe for me to take PAMELOR?

Is it safe for me to take PAMELOR?

PAMELOR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are in the acute recovery period after myocardial infarction or have taken an MAOI in the past 14 days.

PAMELOR Common Side Effects

PAMELOR Common Side Effects

Common side effects of PAMELOR:

  • Blurred vision
  • Dry mouth
  • Nausea
  • Vomiting
  • Loss of appetite
  • Numbness in the hands or feet
  • High blood pressure
  • Rash
  • Itching
PAMELOR Serious Side Effects

PAMELOR Serious Side Effects

Serious side effects are rare with PAMELOR. Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction
  • Worsening depression
  • Suicidal thoughts and behaviors
  • Seizure
  • Chest pain
  • Shortness of breath
  • Serotonin syndrome: Fast heart rate, sweating, muscle stiffness or spasms, fever, confusion
  • Withdrawal: Nausea, vomiting, mood swings, “brain-zaps”
Effects of other drugs, drug classes and over-the-counter products on PAMELOR

Effects of other drugs, drug classes and over-the-counter products on PAMELOR

The following medications may interact with PAMELOR:

  • Administration of reserpine during therapy with a tricyclic antidepressant has been shown to produce a “stimulating” effect in some depressed patients
  • Close supervision and careful adjustment of the dosage are required when PAMELOR is used with other anticholinergic drugs and sympathomimetic drugs
  • Concurrent administration of cimetidine and tricyclic antidepressants can produce clinically significant increases in the plasma concentrations of the tricyclic
  • antidepressant. The patient should be informed that the response to alcohol may be exaggerated
  • A case of significant hypoglycemia has been reported in a type II diabetic patient maintained on chlorpropamide (250 mg/day), after the addition of PAMELOR (125 mg/day)
Who makes PAMELOR?

Who makes PAMELOR?

Novartis Pharmaceuticals

Is PAMELOR safe in pregnancy?

Is PAMELOR safe in pregnancy?

Safe use of PAMELOR during pregnancy and lactation has not been established; therefore, when the drug is administered to pregnant patients, nursing mothers, or women of childbearing potential, the potential benefits must be weighed against the
possible hazards.


What to do if you missed your PAMELOR dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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