Key facts about Orphenadrine
What dosages is Orphenadrine available in?
Orphenadrine is available as a 100 mg extended-release tablet.
What is Orphenadrine used for?
Orphenadrine is a muscle relaxant and is used to relieve muscle discomfort from short-term muscle conditions.
How does Orphenadrine work?
Orphenadrine is a muscle relaxant. It’s unclear how the medication works, but we know that it doesn’t work directly on your muscles. Orphenadrine is thought to relieve muscle pain by working in the nervous system to block nerve signals between your spinal cord and muscles.
How do I take Orphenadrine?
Orphenadrine is typically taken as 100 mg by mouth in the morning and in the evening.
Is it safe for me to take Orphenadrine?
Orphenadrine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have glaucoma, pyloric or duodenal obstruction, stenosing peptic ulcers, prostatic hypertrophy or obstruction of the bladder neck, cardio-spasm (megaesophagus)
or myasthenia gravis.
Orphenadrine Common Side Effects
- Common side effects of Orphenadrine:
- Dry mouth
- Sleepiness
- Headache
- Dizziness
Orphenadrine Serious Side Effects
Serious side effects are rare with Orphenadrine.Contact your healthcare provider immediately if you experience any of the following.
- Accidentally taking too much (overdose): fast heartbeat, flushing, extreme sleepiness, hallucinations, changes in vision, distress, confusion
Effects of other drugs, drug classes and over-the-counter products on Orphenadrine
The following medications may interact with Orphenadrine:
- Confusion, anxiety and tremors have been reported in patients receiving propoxyphene and Orphenadrine concomitantly; as symptoms may be simply due to an additive effect, reduction of dosage and/or discontinuation of one or both agents is recommended in such cases
Who makes Orphenadrine?
Various FDA-approved generic manufacturers
Is Orphenadrine safe in pregnancy?
It is not known if Orphenadrine will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.













